0.05). Anne ve 4. ay bebeklerin sTfR değerleri, ferritin ve MGH ile negatif, RDW ile pozitif istatistiksel anlamlı korelasyon göstermiştir (p<0.05).Soriuç: Maternal demir eksikliğinin yenidoğan (kord) ve 4. aydaki demir durumunu etkilemediği, erken süt çocukluğunda, annenin demir durumundan bağımsız olarak yüksele oranda demir eksikliği/demir eksikliği anemisi geliştiği gösterilmiştir. Aim: It is still contoversial that maternal iron deficiency affects iron status of the newborns and early infants. The aim of this study is to investigate the effect of iron deficiency of late pregnancy on the iron status of the newborns and early infants and to define soluble transferrin receptor (sTfR)'s role in the these assessments. Methods: Seventy-eight pregnant women who were admitted for term delivery in SSK Ege Gynecology and Obstetry Clinics and their 78 full-term babies were included in the study. Erythrocyte indexes, ferritin and sTfR levels were studied both in the mothers (within the last 24 hrs before delivery) and their babies ( umblical cord blood and venous blood at the end of 4th month). Erythrocyte indexes were studied with an automatic coulter (Symex SE, 9000); ferritin and sTfR levels were studied with an immunoturbidimetric method and nephelometric method (Bade Behring, Dutch), respectively. Ferritin< ISng/dl and/or sTfR>1.8 mg/dl were accepted as "iron deficient" both for the mothers and the babies. In addition, Hb<ll g/dl and <10.3 g/dl were accepted as' "iron deficiency anemia" for the mothers and their four months old babies, respectively. Babies born from the mothers whose iron status were assesed were than evaluated prospectively in three groups; Group I: Babies with Maternal Iron Deficiency Anemia (MIDA), Group II: Babies with Maternal Iron Deficiency (MID) and Group Ili.'Control (babies from mothers with normal iron status). Data were calculated on the SPSS 10.0 Windows programme and Kruskall- Wallis, Pearson Correlation test and One-Way Anowa were used for statistical analysis.Values <0.05 were accepted significant. Results: The mean chronological, gestational age and number of pregnancy of the pregnant women were 25.8±3.9 years, 39.9±0.1 weeks and 1.9±0.9, respectively. Mean weight of the babies at birth and at four months were 3375.6±483 g and 7010±750 g respectively. While 38.2% of the babies with MIDA and 33.3% of the babies with MID developed iron deficiency anemia at four months; 47.8% and 21.7% of the babies with normal maternal iron status developed iron deficiency and iron deficiency anemia, respectively ( p<0.05). While all of newborns had normal iron status, 66.6% of overall babies developed either iron deficiency or iron deficiency anemia at their four months. There were no statistical difference within the groups in hematological parameters at cord blood and at 4 months. sTfR values of the mothers and the 4 month old babies showed negative correlation with ferritin and MCH and positive correlatin in RDW Conclusion: It is shown that the iron status of the newborns and the early infants is not influenced by the iron deficiency of their mothers and that iron deficiency anemia and/or iron deficiency is seen in high percentages in early infancy irrespective of the maternal iron status.">
[PDF] Maternal demir eksikliği yenidoğan ve erken süt çocukluğu demir durumunu etkiler mi? | [PDF] Does maternal iron deficiency affect iron status of the newborns and early infants?
0.05). Anne ve 4. ay bebeklerin sTfR değerleri, ferritin ve MGH ile negatif, RDW ile pozitif istatistiksel anlamlı korelasyon göstermiştir (p<0.05).Soriuç: Maternal demir eksikliğinin yenidoğan (kord) ve 4. aydaki demir durumunu etkilemediği, erken süt çocukluğunda, annenin demir durumundan bağımsız olarak yüksele oranda demir eksikliği/demir eksikliği anemisi geliştiği gösterilmiştir.">
0.05). Anne ve 4. ay bebeklerin sTfR değerleri, ferritin ve MGH ile negatif, RDW ile pozitif istatistiksel anlamlı korelasyon göstermiştir (p<0.05).Soriuç: Maternal demir eksikliğinin yenidoğan (kord) ve 4. aydaki demir durumunu etkilemediği, erken süt çocukluğunda, annenin demir durumundan bağımsız olarak yüksele oranda demir eksikliği/demir eksikliği anemisi geliştiği gösterilmiştir. Aim: It is still contoversial that maternal iron deficiency affects iron status of the newborns and early infants. The aim of this study is to investigate the effect of iron deficiency of late pregnancy on the iron status of the newborns and early infants and to define soluble transferrin receptor (sTfR)'s role in the these assessments. Methods: Seventy-eight pregnant women who were admitted for term delivery in SSK Ege Gynecology and Obstetry Clinics and their 78 full-term babies were included in the study. Erythrocyte indexes, ferritin and sTfR levels were studied both in the mothers (within the last 24 hrs before delivery) and their babies ( umblical cord blood and venous blood at the end of 4th month). Erythrocyte indexes were studied with an automatic coulter (Symex SE, 9000); ferritin and sTfR levels were studied with an immunoturbidimetric method and nephelometric method (Bade Behring, Dutch), respectively. Ferritin< ISng/dl and/or sTfR>1.8 mg/dl were accepted as "iron deficient" both for the mothers and the babies. In addition, Hb<ll g/dl and <10.3 g/dl were accepted as' "iron deficiency anemia" for the mothers and their four months old babies, respectively. Babies born from the mothers whose iron status were assesed were than evaluated prospectively in three groups; Group I: Babies with Maternal Iron Deficiency Anemia (MIDA), Group II: Babies with Maternal Iron Deficiency (MID) and Group Ili.'Control (babies from mothers with normal iron status). Data were calculated on the SPSS 10.0 Windows programme and Kruskall- Wallis, Pearson Correlation test and One-Way Anowa were used for statistical analysis.Values <0.05 were accepted significant. Results: The mean chronological, gestational age and number of pregnancy of the pregnant women were 25.8±3.9 years, 39.9±0.1 weeks and 1.9±0.9, respectively. Mean weight of the babies at birth and at four months were 3375.6±483 g and 7010±750 g respectively. While 38.2% of the babies with MIDA and 33.3% of the babies with MID developed iron deficiency anemia at four months; 47.8% and 21.7% of the babies with normal maternal iron status developed iron deficiency and iron deficiency anemia, respectively ( p<0.05). While all of newborns had normal iron status, 66.6% of overall babies developed either iron deficiency or iron deficiency anemia at their four months. There were no statistical difference within the groups in hematological parameters at cord blood and at 4 months. sTfR values of the mothers and the 4 month old babies showed negative correlation with ferritin and MCH and positive correlatin in RDW Conclusion: It is shown that the iron status of the newborns and the early infants is not influenced by the iron deficiency of their mothers and that iron deficiency anemia and/or iron deficiency is seen in high percentages in early infancy irrespective of the maternal iron status.">
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