Rejeneratif Endodontik Tedavi: Bir Literatür Derlemesi

ÖZ: Travma, dental anomaliler, çürük gibi nedenlerle dişler kök oluşumunu tamamlayamadan nekroz olabilirler. Açık apeksli dişlerde endodontik tedaviler birtakım zorluklar barındırmaktadır. Kök duvarlarının kırılgan olması, apeksin açık olması endodontik tedaviyi zorlaştıran sebeplerdendir. Rejeneratif endodontik tedavi nekroz olmuş açık apeksli dişlerde semptomların ortadan kalkmasını, kök gelişiminin devam etmesini, dişlerin vitalite kazanmasını sağlayabilen biyolojik temelli endodontik tedavi seçeneğidir. Rejeneratif endodontik tedavide kök kanalları dezenfekte edildikten sonra kanal içerisinde biyolojik bir iskele oluşturulması sağlanır. Bu iskele büyüme faktörleri ve kök hücrelerin de yardımıyla rejeneratif bir pulpa dokusu oluşturmak için destek görevi görür. Organize pulpa dokusu oluşturulması hedeflense de yapılan araştırmalarda gerçek pulpa dokusu oluşumu kanıtlanmamıştır. Günümüzde bu tedavi immatür nekrotik dişlerin endodontik tedavisinde ilk seçenek olarak önerilmektedir. Bu tedavinin diş sağkalımı üzerinde yüksek başarı oranlarına sahip olduğu birçok çalışmada gösterilmiştir. Bu makalede rejeneratif endodontik tedavi ve bu tedavinin olumlu-olumsuz sonuçlarının güncel literatürdeki yeri derlenmiştir. ABSTRACT: Due to trauma, dental anomalies, caries, etc., the teeth may become necrosis before they can complete their root formation. Endodontic treatments in open apex teeth present some difficulties. The fragility of the root walls and the open apex are among the reasons that complicate the endodontic treatment. Regenerative endodontic treatment is a biological-based endodontic treatment option that can provide relief of symptoms, continuation of root development, and vitality of teeth in necrotic, open apex teeth. In regenerative endodontic treatment, after the root canals are disinfected, a biological scaffold is formed within the canal. This scaffold acts as a support to form a regenerative pulp tissue with the help of growth factors and stem cells. Although it is aimed to create organized pulp tissue, true pulp tissue formation has not been proven in the studies. Today, this treatment is recommended as the first choice in the endodontic treatment of immature necrotic teeth. Many studies have shown that this treatment has high success rates on dental survival. In this article, regenerative endodontic treatment and its positive and negative results in the current literature are reviewed.

Anahtar Kelimeler:

tedavi sonuçları, kök kanal dezenfeksiyonu, rejeneratif endodontik tedavi

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