Staphylococcus aureus rarely causes pyelonephritis or cystitis in children. S. aureus-induced urinary tract infection usually develops after an instrumentation or secondary causes such as renal abscess, osteomyelitis or bacterial endocarditis. Additionally, urinary tract colonization by S. aureus may also be the source of staphylococcal bacteremia associated with urinary tract abnormalities and vesicoureteral reflux. Here, a 5-year-old boy with urinary tract anomaly detected S. aureus in both blood and urine cultures. Diagnosis and treatment process of the patient were presented.
Al Mohajer M, Musher DM, Minard CG, Darouiche RO. Clinical significance of Staphylococcus aureus bacteriuria at a tertiary care hospital. Scand J Infect Dis. 2013;45(9):688–95.
Arpi M, Renneberg J. The clinical significance of Staphylococcus aureus bacteriuria. J Urol. 1984;132(4):697–700.
Demuth PJ, Gerding DN, Crossley K. Staphylococcus aureus bacteriuria. Arch Intern Med. 1979;139(1):78–80.
Muder RR, Brennen C, Rihs JD, Wagener MM, Obman A, Stout JE, et al. Isolation of Staphylococcus aureus from the urinary tract: association of isolation with symptomatic urinary tract infection and subsequent Staphylococcal bacteremia. Clin Infect Dis. 2006;42(1):46–50.
Karakonstantis S, Kalemaki D. Evaluation and management of Staphylococcus aureus bacteriuria: an updated review. Infection. 2018;46(3):293-301.
Schlager TA. Urinary tract infections in children younger than 5 years of age: epidemiology, diagnosis, treatment, outcomes and prevention. Paediatr Drugs. 2001;3(3):219-27.
Lee BK, Crossley K, Gerding DN. The association between Staphylococcus aureus bacteremia and bacteriuria. Am J Med. 1978;65(2): 303–306.
Megged, O. Staphylococcus aureus urinary tract infections in children are associated with urinary tract abnormalities and vesicoureteral reflux. Pediatr Nephrol. 2014;29(2):269-72.
Tong SYC, Davis JS, Eichenberger E, Holland TL, Fowler VG. Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management. Clinical Microbiology Reviews. 2015;28(3): 603-61.
Berrocal T, Lopez-Pereira P, Arjonilla A, Gutierrez J. Anomalies of the Distal Ureter, Bladder, and Urethra in Children: Embryologic, Radiologic, and Pathologic Features. Radio Graphics. 2002;22(5): 1139-164.