Buket DEMİRCİ, İmran Kurt ÖMÜRLÜ, Duygu GÜLER, Alparslan ÜNSAL, Ayşe İpek Akyüz ÜNSAL, Selda Demircan SEZER

Maternal faktörlerin prematür retinopatisindeki olası rolü

Amaç: Maternal parametrelerin Prematüre Retinopatisi (ROP) gelişimindeki olası etkilerini araştırmak. Gereç ve yöntem: Merkezimizde doğmuş prematürelerin annelerinin gebelik yaşları, beden kitle indeksleri (BKİ), gebelik sayısı, kaçıncı gebelik olduğu, erken membran rüptürü (EMR) ve preterm eylem gelişimi, gestasyonel diabet tanısı, sigara ve ilaç kullanımı, doğumdan hemen önceki sistolik ve diastolik kan basınçları, kan şekeri, kan sayımı, karaciğer ve böbrek fonksiyon parametreleri ve obstetrik ultrason bulguları araştırıldı. ROP gelişen ve gelişmeyenler arasında bulgular karşılaştırıldı. Bulgular: ROP gelişen 98 bebeğin ortalama gebelik haftası 29,61±3,45 iken, ROP gelişmeyen 41 bebeğin ise 32,14±2,15 haftaydı. Anne gebelik yaşı, BKİ, gebelik sayısı, gebelik sıralaması, gestasyonel diabet tanısı, preterm eylem, sigara kullanımı, doğumdan hemen önceki sistolik ve diastolik kan basınçları, hemoglobin, hematokrit, üre, kreatinin, ALT, AST değerleri arasında gruplar arası anlamlı fark yokken (p>0,05); Evre 1 ve Evre 3’deki ROP grupları arasında kan şekeri açısından istatistiksel fark saptandı (p=0,016). Oligohidroamnios, fetal distres, intrauterin gelişme geriliği, plasenta dekolmanı ve patolojik Doppler US parametreleri gibi patolojik US bulgusu varlığında %75,8 oranında ROP görüldüğü, EMR gelişenlerin %83,3’ünde de ROP geliştiği saptandı (sırasıyla p

The probable role of maternal factors on retinopathy of prematurity

Purpose: To investigate the potential effects of maternal factors on development of Retinopathy of Prematurity (ROP). Material and method: Age, BMI, number of gestations, rank of gestation, early membrane rupture (EMR) or preterm labour, gestational diabetes, tobacco or drug usage, blood pressure, glucose level, complete blood count and renal-hepatic parameters and obstetric ultrasound (US) findings of mothers of prematures followed in our center were investigated. Results were compared between ROP positive and negative prematures. Results: Average gestational week of ROP positive (n=98) and negative (n=41) prematures were 29.61±3.45 and 32.14±2.1 weeks, respectively. No significant difference was present between maternal age, BMI, number of gestations, rank of gestation, EMR or preterm labour, gestational diabetes, tobacco or drug usage, blood pressure, CBC and renal-hepatic parameters of study groups (p>0.05). Glucose levels of stage 1 and stage 3 ROP groups were significantly different (p=0.016). ROP was present in 75.8% of cases who had obstetric US findings such as oligohidroamnios, fetal distress, intrauterine growth retardation, placental problems and pathological Doppler parameters (p

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