Recep BAYDEMİR, Hümeyra ASLANER, Gamze KALIN ÜNÜVAR, Murat GÜLTEKİN, Şeyma BENLİ, Ali Ramazan BENLİ

COVID-19 Hastalarında İnme Sıklığının Değerlendirilmesi

Amaç: Koronavirüs hastalığı 2019 (COVID-19) hastalarında merkezi ve periferik sinir sisteminin farklı mekanizmalarla tutulumuna bağlı olarak nörolojik semptomlar ortaya çıkmaktadır. COVID-19 enfeksiyonunda sitokin artışı ile birlikte protrombotik aktivasyon ile mikrovasküler tromboz gelişmektedir. Bu çalışmada COVID-19 pozitif hastalarda serebrovasküler hastalık insidansını ve eşlik eden risk faktörlerini araştırmayı amaçladık.

Anahtar Kelimeler:

COVID-19, inme, serebrovasküler hastalıklar

Evaluation of Stroke Frequency in COVID-19 Patients

Objective: Neurological symptoms occur due to central and peripheral nervous system involvement with different mechanisms in coronavirus disease 2019 (COVID-19). Microvascular thrombosis develops with prothrombotic activation along with the increase in cytokines in COVID-19 infection. We aimed to investigate the incidence of cerebrovascular disease and concomitant risk factors in COVID-19 positive patients.

Keywords:

COVID-19, stroke, cerebrovascular diseases,

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Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-506. doi:10.1016/S0140-6736(20)30183-5
Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study. Lancet. 2020;395(10223):507-513. doi:10.1016/S0140-6736(20)30211-7
Garg RK. Spectrum of neurological manifestations in Covid-19: A review. Neurol India. 2020;68(3):560-572. doi:10.4103/0028-3886.289000
Lyden P. Temporary emergency guidance to US stroke centers during the COVID-19 pandemic on behalf of the AHA/ASA Stroke Council Leadership. Stroke. 2020;51(6):1910-1912. doi:10.1161/STROKEAHA.120.030023
Yang X, Yu Y, Xu J, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: A single-centered, retrospective, observational study. Lancet Respir Med. 2020;8(5):475-481. doi:10.1016/S2213-2600(20)30079-5
Tang N, Li D, Wang X, Sun Z. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost. 2020;18(4):844-847. doi:10.1111/jth.14768
Mao L, Jin H, Wang M, et al. Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China. JAMA Neurol. 2020;77(6):683-690. doi:10.1001/jamaneurol.2020.1127
Beyrouti R, Adams ME, Benjamin L, et al. Characteristics of ischaemic stroke associated with COVID-19.J Neurol Neurosurg Psychiatry. 2020;91(8):889-891. doi: 10.1136/jnnp-2020-323586
Alger HM, Rutan C, Williams JH, et al. American Heart Association COVID-19 CVD registry powered by get with the guidelines. Circ Cardiovasc Qual Outcomes. 2020;13(8):e006967. doi:10.1161/CIRCOUTCOMES.120.006967
Qureshi AI, Baskett WI, Huang W, et al. Acute ischemic stroke and COVID-19: An analysis of 27676 patients. Stroke. 2021;52(3):905-912. doi:10.1161/STROKEAHA.120.031786
Ramos-Araque ME, Siegler JE, Ribo M, et al. Stroke etiologies in patients with COVID-19: The SVIN COVID-19 multinational registry. BMC Neurol. 2021;21(1):1-11. doi:10.1186/s12883-021-02075-1
Paterson RW, Brown RL, Benjamin L, et al. The emerging spectrum of COVID-19 neurology: Clinical, radiological and laboratory findings. Brain. 2020;143(10):3104-3120. doi:10.1093/brain/awaa240
Kumar J, Makheja K, Rahul F, et al. Long-term neurological impact of COVID-19. Cureus. 2021;13(9):3-7. doi:10.7759/cureus.18131
Zakeri A, Jadhav AP, Sullenger BA, Nimjee SM. Ischemic stroke in COVID-19 positive patients: An overview of SARS-CoV-2 and thrombotic mechanisms for the neurointerventionalist. J Neurointerv Surg. 2021;13(3):202-206. doi:10.1136/neurintsurg-2020-016794
Qin C, Zhou L, Hu Z, et al. Clinical characteristics and outcomes of COVID-19 patients with a history of stroke in Wuhan, China. Stroke. 2020;51(7):2219-2223. doi:10.1161/STROKEAHA.120.030365
Yaghi S, Ishida K, Torres J, et al. SARS-CoV-2 and stroke in a New York healthcare system. Stroke. 2020;51(7):2002-2011. doi:10.1161/STROKEAHA.120.030335
Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study. Lancet. 2020;395(10229):1054-1062. doi:10.1016/S0140-6736(20)30566-3