This year there are seven articles in our first issue, 6 original and one compilation. Original articles are as follows;Patients with constipation and related factors study the aim of are to assess the etiologic causes, clinical features and factors related to constipation among cases attending with constipation complaints. In other study, examinations and treatments of patients hospitalized in the clinic with the complaint of corrosive substance ingestion were examined. The researcher in the study about the obstetrics to appoint the risk of stillbirth and the other adverse maternal and perinatal outcomes in women of AMA (Advanced maternal age) that traditionally described as pregnancy in women aged 35 years or older. Also, in another research about the obstetrics, the researcher was conducted to determine osteoporosis health beliefs and self-efficacy of Turkish women and to investigate the relationship between women’s characteristics with osteoporosis health beliefs and self-efficacy.In other study the researches in cardiology and eye had together was to evaluate the relationship between the retinal findings and coronary artery disease by performing fundoscopic examination in patients diagnosed with coronary artery disease.Our last article is on the field of microbiology analysis of the widely used antibiotics all susceptibility testing results from Escherichia coli (E. coli) cultured from clinical specimens’ private hospital was performed.In this issue the subject about the challenge of pathological diagnosis for precancerous cervical Lesions has been submitted as the compilation. Many thanks to the authors, referees and editorial board who contributed to this issue hope to meet again in different and new issues you have pleasure while reading…