The relationship between obesity and restless legs syndrome

Restless legs syndrome (RLS) has been shown to be more common in obese than in non-obese people in many studies. The aim of this study was to investigate passible relationship between obesity and seconder RLS prevalence and severity in the Turkish population. Method: A total of 70 volunteers were included in the study. Of these 44 were obese (BMI≥30 kg/m2) and 26 were non obese(BMI

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Allen RP, Picchietti D, Hening WA, et al. Restless legs syndrome: diagnostic criteria, special considerations and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med. 2003;4:101-19.

Garcia-Borreguero D, Odin P, Schwarz C. Restless legs syndrome: an overview of the current understanding and management. Acta Neurol Scand. 2004;109:303-17.

International Restless Legs Syndrome Study Group 2012. Revised diagnostic criteria. Available from http://irlssg.org/diagnostic -criteria/

Allen RP, Walters AS, Montplaisir J, et al. Restless legs syndrome (RLS) prevalence and impact: REST (RLS epidemiology, symptoms and treatment) general population study. Arch Intern Med. 2005;165:1286-92.

Allen R. Dopamine and iron in the pathophysiology of restless legs syndrome. Sleep Med. 2004;5:385-91.

Takaki J, Nishi T, Nangaku M, et al. Clinical and psychological aspects of restless legs syndrome in uremic patients on hemodialysis. Am J Kidney Dis. 2003;41:833-9.

Allen RP. Controversies and challenges in defining the etiology and pathophysiology of restless legs syndrome. Am J Med. 2007;120:13-21.

Wang GJ, Volkow ND, Logan J, et al. Brain dopamine and obesity. Lancet. 2001;357:354-7

Elwood P, Hack M, Pickering J, et al. Sleep Disturbance, stroke and heart disease events: evidence from the Caerphilly cohort. J Epidemiol. Community Health. 2006;60:69-73.

Hargens TA, Kaleth AS, Edwards ES, et al. Assosiation between sleep disorders, obesity and exercise: a review. Nat Sci Sleep. 2013;5:27-35.

Wang Y, Beydoun MA. The obesity epidemic in the United States-gender, age, socioeconomic, racial/ethnic and geographic characteristics: a systematic review and meta-regression analysis. Epidemiol Rev. 2007;29:6-28.

Batool-Anwar S, Li Y, De Vito K, et al. Lifestyle factors and risk of restless legs syndrome: prospective cohort Study. J Clin Sleep Med. 12,187-94.

Gao X, Micheal A, Schwarzschild MD, et al. Obesity and restless legs syndrome in men and women. Neurology. 2009:72;1255-61.

Schilling C, Schredl M, Strobl P, et al. Restless legs syndrome: evidence for nocturnal hypothalamic-pituitary-adrenal system activaton. Mov Disord. 2010;25:1047-52.

Spath-Schwalbe E, Gofferje M, Kern W, et al. Sleep disruption alters nocturnal ACTH and cortisol secretory patterns. Biol Psychiatry. 1991;29:575-84.

Högl B. Circadian rhythms in restless legs syndrome. Sleep Med. 2006:7;20910.

Early CJ, B Barker P, Horská A, et al. MRI-determined regional brain iron concentrations in early and late-onset restless legs syndrome. Sleep Med. 2006;7:458.

Allen R, Early C. Defining the phenotype of the restless legs syndrome using age-of-symptom-onset. Sleep Med. 2000;1:11-9.

Allen RP. Restless leg syndrome / Willis-Ekbom disease pathophysiology. Sleep Med Clin. 2015;10:207-14.

Zhao L, Zhang X, Shen Y, et al. Obesity and iron deficiency: a quantitative meta-analysis. Obes Rev. 2016:16;1081-93.

Wang GJ, Volkow ND, Logan J et al. Brain dopamine and obesity. Lancet. 2001;357:354-7.

Salas RE, Gamaldo CE, Allen RP. Update in restless legs syndrome. Curr Opin Neurol. 2010;23:401-6.

Concor JR, Wang XS, Allen RP, et al. Altered dopaminergic profile in the putamen and substantia nigra in restless leg syndrome. Brain 2009;132:2403-12.

Kim J, Choi C, Shin K, et al. Prevalence of restless legs syndrome and associated factors in the Korean adult population: the Korean Health and Genome Study. Psychiatry Clin Neurosciç 2005;59:350-3.

De Vito K, Yanping L, Batool-Anwar S, et al. Prospective study of obesity, hypertension, high cholesterol and risk of restless legs syndrome. Mov Disord. 2014:29;1044-52.

Lin S, Zhang H, Gao T, et al. The assosiation between obesity and restless legs syndrome: A systemic review and meta-analysis of observational studies. J Affect Disord. 2018;235:384-91.

Yıldız D, Buyukkoyuncu N, Kilic A, et al. Obesity: a possible risk factor for restless legs syndrome. Neurol Res. 2017;39:1044-8.

Benediktsdottir B, Janson C, Lindberg E, et al. Prevalence of restless legs syndrome among adults in Iceland and Sweden: Lung function, comorbidity, ferritin, biomarkers and quality of life. Sleep Med. 2010;11:1043-8.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: 4
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
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