Investigation of rotavirus and enteric adenovirus antigens in children between 0-14 years old

Acute gastroenteritis (AGE) is an important cause of mortality and morbidity, especially in children. Rotavirus, norovirus, and adenovirus are the most common viral AGE agents in Turkey. We aimed to investigate of rotavirus and adenovirus antigens in children between 0-14 years old with acute gastroenteritis admitted to the Bolu Abant İzzet Baysal University Training and Research Hospital. Rotavirus and adenovirus antigens were investigated by a combo rapid immunochromatographic diagnostic test (Eco test®, United Kingdom) in a total of 2,675 stool samples. One or more viruses were detected in 238 (8.9%) stool samples. Rotavirus antigen was detected in 191 (7.14%) stool specimens and adenovirus antigen were detected in 47 (1.75%) stool specimens. Both virus antigens were detected positive in 13 (6.8%) the stool samples. The detected rotavirus antigen positivity was higher under the age of 5 than other age groups; a statistically significant difference was found between age groups (p< 0.05; p< 0.00). In conclusion, rotavirus and adenovirus-associated AGE were most commonly found in the age group between 0–5 in this study. Also, the prevalence rates of viral AGE were found to be lower in the authors’ region when compared to other regions, probably due to the higher rates of rotavirus vaccination.

Kaynakça

1. Chow CM, Leung AK, Hon KL. Acute gastroenteritis: from guidelines to real life. Clin Exp Gastroenterol. 2010;3:97–112.

2. Turkey Fourth Population Conference, Ankara, 2015. Available at:http:// www.hips.hacettepe.edu.tr/TNBK-2015_Tam_Metinler_Kitabi.pdf. Accessed date: 15 December, 2019.

3. Koletzko S, Osterrieder S. Acute infectious diarrheae in children. Dtsch Arztebl Int 2009;106: 539-48.

4. Turkey Public Health Association 2016 Annual Report. Available at:https:// hsgm.saglik.gov.tr/depo/kurumsal/plan-ve-faaliyetler/2016-faaliyetraporu.pdf. Accessed date: 15 December, 2019.

5. Akhter S, Türegün B, Kıyan M, et al. Investigation of seven different RNA Viruses associated with gastroenteritis in children under five years old. Mikrobiyol Bul. 2014;48:233-41.

6. Parashar UD, Hummelman EG, Bresee JS, et al. Global illness and deaths caused by rotavirus disease in children. Emerg Infect Dis. 2003;9:565–72. 7. Bányai K, Estes MK, Martella V, et al. Viral gastroenteritis. Lancet. 2018;392:175-86.

8. McHaile DN, Philemon RN, Kabika S et al. Prevalence and genotypes of Rotavirus among children under 5 years presenting with diarrhea in Moshi, Tanzania: A hospital based cross sectional study. BMC Res Notes. 2017;10: 4-9.

9. Badani AA, Areqi AL, Majily A, et al. Rotavirus diarrhoea among children in Taiz, Yemen: prevalence risk factors and detection of genotypes. Int J Pediatr. 2014;2014:1–9.

10. Nakawesi JS, Wobudeya E, Ndeezi G, et al. Tumwine JK. Prevalence and factors associated with rotavirus infection among children admitted with acute diarrhea in Uganda. BMC Pediatr. 2010;10:2-6.

11. Tayeb HT, Balkhy HH, Aljuhani SM, et al. Increased prevalence of rotavirus among children associated gastroenteritis in Riyadh Saudi Arabia. Virol J. 2011;8:548.

12. Çakır F, Özcan N, Şahin Hİ et al. Rotavirus and enteric adenovirus detection among diarrheic outpatients in a tertiary hospital. Int Arch Med Res. 2018;10:7-13.

13. Kırdar S, Kahyaoğlu F, Yazıcı V, et al. Investigation of The Agents of Viral Gastroenteritis by PCR İn Stool Specimens with Rota/Adenovirus Positive by Antigen Test. J Biotechnol Strateg Heal Res. 2017;1:88-93.

14. Dağı HT, Fındık D. Investigation of rotavirus and adenovirus antigens in patients with acute gastroenteritis. J Clin Exp Investig. 2015;5:256-60.

15. Gulen D, Aydin M, Uzun A, Kaya AD. Presence of rotavirus and adenovirus antigens in children with gastroenteritis who attended the tekirdag state hospital. J Pediatr Inf. 2013;7:131-5.

16. Çaycı YT, Yılmaz G, Birinci A. Investigation of the frequency of rotavirus and adenovirus in acute gastroenteritis cases. Pamukkale Med J.. 2017;10:61-5.

17. Tekin M, Topaloglu N, Yıldırım Ş et al. Frequency of rotavirus in children with acute gastroenteritis. Int J Clinic Res. 2014;2:18-20.

18. Tapisiz A, Demirdag TB, Cura Yayla BC et al.Rotavirus infections in children in Turkey: A systematic review. Rev Med Virolog. 2019;29,e2020.

19. Koksal T, Akelma AZ, Koksal AO et al.Cost-effectiveness of rotavirus vaccination in Turkey. J Microbiol, Immunol Infect. 2017; 5:693–99.

20. Otag F, Direkel Ş, Özgür D, et al. Investigation of rotavirus and enteric adenovirus antigens in pediatric patient with acute gastroenteritis by rapid immunochromatographic method. Mersin Üniversitesi Sağlık Bilim Dergisi. 2012;5:18-23.

21. Ozsari T, Bora G, Kaya B, Yakut K. The prevalence of rotavirus and adenovirus in the childhood gastroenteritis. Jundishapur J Microbiol. 2016;9:e34867.

22. Özer B, Jenedi K, Pehlivanoğlu C,et al. A rotavirus and adenovirus prevelance in stool samples of patients with acute gastroenteritis. Mustafa Kemal Üniversitesi Tıp Derg. 2015;5:1-10.

23. İnci A, Kurtoglu MG, Baysal B. Bir eğitim ve araştırma hastanesinde rotavirus gastro-enteriti prevalansının araştırılması. İnfeksiyon Derg. 2009;23:79-82.

24. Kurtoglu MG, İnci A, Özdemir M, ve ark. Çocukluk yaş grubunda adenovirus gastroenteritlerinin mevsimlere ve yaşlara göre dağılımı. Turk Mikrobiyol Cem Derg. 2010; 40:157–62.

Kaynak Göster

Medicine Science
  • ISSN: 2147-0634
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2012

13.8b7.7b

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