Evaluation of Left Ventricular Function of Patients with Irritable Bowel Syndrome with Tissue Doppler and 2D Speckle Tracking Echocardiography

We aimed to evaluate the systolic and diastolic functions of left ventricule in irritable bowel syndrome (IBS) by conventional echocardiography and two-dimensional (2D) speckle tracking echocardiography (STE) method. Thirty patients with IBS diagnosed with Rome III criteria were referred to our clinic. Standart echocardiographic and 2D-STE evaluation were obtained from all participants. C-reactive protein and erythrocyte sedimentation rate showing inflammation were significantly higher in patients with IBS compared to control group. Comparision of echocardiographic and tissue doppler imaging parameters measured from the septal mitral annulus demonstrated similar values between both groups. There were not any differences between the groups in terms of SRS-3C, SRE-4C, SRE-3C, SRE-2C, GLSRE, SRA-4C, SLA-3C, SLA-2C and GLSRA (p>0.05, for all). GLS (p=0.002), GLSRS (p=0.021), SRS-2C (p=0.030), S-4C (p=0.001), S-3C (p=0.025) and S-2C (p=0.012) values were significantly lower in IBS patients than in the control group. Our results suggest that IBS of which pathogenesis cannot be clearly elucidated is an inflammatory process and the heart may also be affected from this process. 2D-STE can also be useful in determination of subclinical left ventricular dysfunction in IBS patients

___

1. Hanestad BR. Quality of life and insulin dependent diabetes mellitus. University of Bergen, Bergen, 1992;36.

2. Engsbro AL, Simrén M, Bytzer P. The Rome II and Rome III criteria identify the same subtype-populations in irritable bowel syndrome: agreement depends on the method used for symptom report. Neurogastroenterol Motil. 2012;24(7):604-11,e266.

3. Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Müller-Lissner SA. Functional bowel disorders and functional abdominal pain. Gut. 1999;45 Suppl 2:II43-7.

4. Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology. 2006;130(5):1480-91.

5. Pae CU, Masand PS, Ajwani N, Lee C. Irritable bawel syndrome in psychiatric perspective: A comprehensive review. Int J Clin Pract. 2007;61(10):1708-18.

6. Catanzaro R, Occhipinti S, Calabrese F, Anzalone MG, Milazzo M, Italia A, Marotta F. Irritable bowel syndrome: new findings in pathophysiological and therapeutic field. Minerva Gastroenterol Dietol. 2014;60(2):151-63.

7. Liu Q, Wang EM, Yan XL, Chen SL. Automatic functioning in irritable bowel syndrome as measured by heart rate variability: a meta-analysis. J Dig Dis. 2013;14(12):638-46.

8. Teske AJ, De Boeck BW, Melman PG, Sieswerda GT, Doevendans PA, Cramer MJ. Echocardiographic quantification of myocardial function using tissue deformation imaging, a guide to image acquisition and analysis using tissue Doppler and speckle tracking. Cardiovasc Ultrasound. 2007;5:27.

9. Teichholz LE, Kreulen T, Herman MV, Gorlin R. Problems in echocardiographic volume determinations: echocardiographic-angiographic correlations in the presence of absence of asynergy. Am J Cardiol. 1976;37(1):7-11.

10. Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, Flachskampf FA, Foster E, Goldstein SA, Kuznetsova T, Lancellotti P, Muraru D, Picard MH, Rietzschel ER, Rudski L, Spencer KT, Tsang W, Voigt JU. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2015;28(1):1-39.e14.

11. Collins SM. Is the irritable gut an inflamed gut? Scand J Gastroenterol Suppl. 1992;192:102-5.

12. Wilder-Smith CH, Schindler D, Lovblad K, Redmond SM, Nirkko A. Brain functional magnetic resonance imaging of rectal pain and activation of endogenous inhibitory mechanisms in irritable bowel syndrome patient subgroups and healthy controls. Gut. 2004;53(11):1595–601.

13. van Orshoven NP, Andriesse GI, van Schelven LJ, Smout AJ, Akkermans LM, Oey PL. Subtle involvement of the parasympathetic nervous system in patients with irritable bowel syndrome. Clin Auton Res. 2006;16(1):33-9.

14. Jarrett ME, Burr RL, Cain KC, Hertig V, Weisman P, Heitkemper MM. Anxiety and depression are related to autonomic nervous system function in women with irritable bowel syndrome. Dig Dis Sci. 2003;48(2):386-94.

15. Heitkemper M, Burr RL, Jarrett M, Hertig V, Lustyk MK, Bond EF. Evidence for autonomic nervous system imbalance in women with irritable bowel syndrome. Dig Dis Sci. 1998;43(9):2093-8.

16. Karling P, Nyhlin H, Wiklund U, Sjöberg M, Olofsson BO, Bjerle P. Spectral analysis of heart rate variability in patients with irritable bowel syndrome. Scand J Gastroenterol. 1998;33(6):572-6.

17. Schäfermeyer A, Gratzl M, Rad R, Dossumbekova A, Sachs G, Prinz C. Isolation and receptor profiling of ileal enterochromaffin cells. Acta Physiol Scand. 2004;182(1):53-62.

18. Furlan R, Colombo S, Perego F, Atzeni F, Diana A, Barbic F, Porta A, Pace F, Malliani A, Sarzi-Puttini P. Abnormalities of cardiovascular neural control and reduced orthostatic tolerance in patients with primary fibromyalgia. J Rheumatol. 2005;32(9):1787-93.

19. Higham PD. Campbell RW. QT dispersion. BR Heart J. 1994;71(6):508-10.

20. Binnetoğlu FK, Yıldırım Ş, Topaloğlu N, Tekin M, Kaymaz N, Aylanç H, Karakurt H. Early detection of myocardial deformation by 2D speckle tracking echocardiography in normotensive obese children and adolescents. Anadolu Kardiyol Derg. 2015;15(2):151-7.

21. Altiok E, Neizel M, Tiemann S, Krass V, Becker M, Zwicker C, Koos R, Kelm M, Kraemer N, Schoth F, Marx N, Hoffmann R. Layer-specific analysis of myocardial deformation for assessment of infarct transmurality: comparison of strain-encoded cardiovascular magnetic resonance with 2D speckle tracking echocardiography. Eur Heart J Cardiovasc Imaging. 2013;14(6):570-8.

22. Demirelli S, Degirmenci H, Bilen H, Ermis E, Duman H, Arisoy A, Bakirci EM, Ipek E, Askin L. Left ventricular mechanics in Behcet's disease: a speckle tracking echocardiographic study. Bosn J Basic Med Sci. 2014;14(3):160-4.

23. Sitia S, Tomasoni L, Cicala S, Atzeni F, Ricci C, Gaeta M, Sarzi-Puttini P, Turiel M. Detection of preclinical impairment of myocardial function in rheumatoid arthritis patients with short disease duration by speckle tracking echocardiography. Int J Cardiol. 2012;160(1):8-14.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
Sayıdaki Diğer Makaleler

Investigation of Extended-Spectrum Beta-Lactamase (Esbl) in Nosocomial Gram-Negative Bacterial Isolates by Different Test Methods

FİLİZ ORAK, Akgün YAMAN, Gülşah ŞEYDAOĞLU

Hemostasis, Disorders of Coagulation and Transfusion in Cirrhosis

A Cyriac Abby PHİLİPS, Prasanta MUKHOPADHYAY

Thyroid Gland Hemiagenesis with Multinodular Graves' Disease: A Case Report

Ayşe ARDUÇ, Mazhar Müslüm TUNA, Berçem AYÇİÇEK DOĞAN, Gülhan AKBABA, DİLEK BERKER, Serdar GÜLER

Seizure Due To Hypocalcemia Caused by Late Onset Hypoparathyroism after Thyroid Surgery

Dilek ARPACI, Mehmet YILDIRIM, Nehir CEYLAN, Hasan ERGENÇ, Aysel GÜRKAN, Ali TAMER

A Viral Outcome

Cyriac Abby PHİLİPS

Regional Differences in the Prevalence of Hypertension in Turkey

Mustafa ALDEMİR, MEHMET BİLGEHAN PEKTAŞ, Ali İhsan PARLAR, Sadık Volkan EMREN, İsmet DOĞAN

Evaluation of Left Ventricular Function of Patients with Irritable Bowel Syndrome with Tissue Doppler and 2D Speckle Tracking Echocardiography

Hakan TAŞOLAR, Selami DEMİRELLİ, Havva YILMAZ, Esra POYRAZ, Hüsnü DEĞİRMENCİ, Mehmet BALLI, Mustafa ÇETİN

Communication Skills, Empathic Tendency and Affecting Factors of Assistant Doctors in Inonu Universty, Faculty of Medicine, Malatya

Çiğdem BOZKIR, Çiğdem TEKİN, Burak METE, Erkay NACAR, Ali ÖZER

Pre-opereative Parathormone Levels are Correlated with Mean Diameter of Parathyroid Adenoma and Pre-operatıve Serum Calcium and Alkaline Phosphatase Levels

Gülşah ELBÜKEN, Recep AKTİMUR, Kadir YILDIRIM, Sude Hatun AKTİMUR, MEHMET DERYA DEMİRAĞ, Aysu Başak ÖZBALCI, Mustafa BAKIRTAŞ, Banu KİRTİLOGLU, NURAYDIN ÖZLEM

Transverse Testicular Ectopia: A Case Report

Caner Ediz, Bayram KAHRAMAN, Cemal TAŞDEMİR