Evaluation of fundus findings in preeclampsia

Bu çalışmada preeklampsi hastalarındaki fundus muayene bulgularının değerlendirilmesi amaçlanmıştır. Haziran 2007-Şubat 2016 tarihleri arasında preeklampsi tanısıyla Mersin Üniversitesi Hastanesine yatırılan ve görme bulanıklığı nedeniyle konsülte edilen 45 hastanın fundus bulguları retrospektif olarak değerlendirildi. Çalışmaya dahil edilen hastaların yaş ortalaması 28.6 ± 6.18 yıl iken, ortalama gebelik haftası 32.95 ± 4.22 idi. Tüm hastaların ön segment muayenesi normaldi. Otuz beş hastanın fundus bulguları normal olarak değerlendirilirken, on (%22.2) hastada patolojik bulgular saptandı. Altı (%60) hastada tek ya da iki taraflı seröz retina dekolmanı izlendi. Ayrıca dört (%40) hastada retinal kanamalar ve eksüdasyonlar görüldü. Fundus bulgularına ek olarak beş (%11.11) hastada geri dönüşümlü posterior lökoensefolopati sendromu saptandı. Altı hasta normal vajinal yolla doğum yaparken otuz dokuz hasta sezaryen ile doğurtuldu. Doğum sonrası hastalarda seröz retina dekolmanı ve fundus bulgularının gerilediği izlendi. Sonuç: Preeklampsi multisistemik bir hastalıktır ve aynı zamanda görsel yollarıda etkileyebilmektedir. Preeklampsili hastalarda fotopsi, görme alanı defektleri, bulanık görme ve bazı olgularda ciddi görme kaybını da içeren görsel semptomlar gelişebilmektedir. Bulanık görme en sık rastlanan görsel şikayettir. Bu hastalarda hipertansif retinopati, eksüdatif retina dekolmanı ve kortikal körlük izlenebilmektedir. Ancak görme kaybıyla başvuran hastaların tamamının fundus muayenesinde patolojik bulgular izlenmemektedir. Preeklampsi ile ilişkili retinal bulgular genellikle ek bir tedavi ihtiyacı olmadan doğumla birlikte gerileme göstermektedir

Preeklampside fundus bulgularının değerlendirilmesi

In this study aimed to evaluate of the fundus examination findings in the patients with preeclampsia. Fundus findings of 45 patients hospitalized in Mersin University Hospital due to preeclampsia and consulted with blurred vision between June 2007 and February 2016 were evaluated retrospectively. The average age of patients was 28.6 ± 6.18 years and mean gestational age was 32.95 ± 4.22. Anterior segment examination was normal in all patients. The fundus findings of thirty five patients were assessed as normal, but pathological findings were detected in ten (%22.2) patients. Unilateral or bilateral serous retinal detachment was observed in six (%60) patients. Retinal hemorrhages and exudates were seen in four (%40) patients. In addition to the fundus findings reversible posterior leucoencephalopathy syndrome was detected in 5 patients. Six patients were delivered vaginally while thirty-nine patients with cesarean section. Serous retinal detachment and fundus findings regressed after delivery in patients. The preeclampsia syndrome is a multisystem disorder and it also can affect the visual pathways. Visual symptoms in preeclampsia include photopsia, visual field defects, blurred vision and, in severe cases, serious blindness. Blurred vision is the most common visual complaint. Hypertensive retinopathy, exudative retinal detachment and cortical blindness can be seen in patients. But in fundus examination pathological findings are not observed in all of the patients admitted with vision loss. Preeclampsia related retinal findings generally resolves after delivery and no additional treatment is required

___

  • 1. Steegers EA, von Dadelszen P, Duvekot JJ, Pijnenborg R. Preeclampsia. Lancet. 2010;376(9741):631-44.
  • 2. Wallis AB, Saftlas AF, Hsia J, Atrash HK. Secular trends in the rates of preeclampsia, eclampsia, and gestational hypertension, United States, 1987-2004. Am J Hypertens. 2008;21(5):521-26.
  • 3. Kuklina EV, Ayala C, Callaghan WM. Hypertensive disorders and severe obstetric morbidity in the United States. Obstet Gynecol. 2009;113(6):1299-306.
  • 4. Publications Committee The Society for Maternal-Fetal Medicine, Sibai BM. Evaluation and management of severe preeclampsia before 34 weeks’ gestation. Am J Obstet Gynecol. 2011;205(3):191-8.
  • 5. Royburt M, Seidman DS, Serr DM, Mashiach S. Neurologic involvement in hypertensive disease of pregnancy. Obstet Gynecol Surv. 1991;46(10):656-64.
  • 6. Roos NM, Wiegman MJ, Jansonius NM, Zeeman GG. Visual disturbances in (pre)eclampsia. Obstet Gynecol Surv. 2012;67(4):242-50.
  • 7. Yılmaz A, Pata Ö, Öz Ö, Yıldırım Ö, Dilek S. Bilateral serous detachment in preeclampsia. Ret-Vit. 2005;13(3):307-10.
  • 8. Kurdoğlu Z, Kurdoğlu M, Ay G, Yaşar T. Retinal findings in cases of preeclampsia. Perinatal Journal. 2011;19(2):60-3.
  • 9. Kim JW, Park MH, Kim YJ, Kim YT. Comparison of subfoveal choroidal thickness in healthy pregnancy and pre-eclampsia. Eye. 2016;30(3):349-54.
  • 10. Garg A, Wapner RJ, Ananth CV, Dale E, Tsang SH, Lee W, Allikmets R, Bearelly S. Choroidal and retinal thickening in severe preeclampsia. Invest Ophthalmol Vis Sci. 2014;55(9):5723-9.
  • 11. Schultz KL, Birnbaum AD, Goldstein DA. Ocular disease in pregnancy. Curr Opin Ophthalmol. 2005;16(5):308-14.
  • 12. Sunness JS. The pregnant woman’s eye. Surv Ophthalmol. 1988;32(4):219-38.
  • 13. Abu Samra K. The eye and visual system in the preeclampsia/eclampsia syndrome: What to expect? Saudi J Ophthalmol. 2013;27(1):51-3.
  • 14. Celik H, Avci B, Isik Y. Vascular endothelial growth factor and endothelin-1 levels in normal pregnant women and pregnant women with pre-eclampsia. J Obstet Gynaecol. 2013;33(4):355-8.
  • 15. Levine RJ, Maynard SE, Qian C, Lim KH, England LJ, Yu KF, Schisterman EF, Thadhani R, Sachs BP, Epstein FH, Sibai BM, Sukhatme VP, Karumanchi SA. Circulating angiogenic factors and the risk of preeclampsia. New Engl J Med. 2004;350(7):672-83.
  • 16. Heilmann L, Rath W, Pollow K. Hemostatic abnormalities in patients with severe preeclampsia. Clin Appl Thromb Hemos. 2007;13(3):285-91.
  • 17. Jaffe G, Schatz H. Ocular manifestations of preeclampsia. Am J Ophthalmol. 1987;103(3):309-15.
  • 18. Katsimpris JM, Theoulakis PE, Manolopoulou P. Bilateral serous retinal detachment in a case of preeclampsia. Klin Monbl Augenheilkd. 2009;226(4):352-4.
  • 19. Hayreh SS, Servais GE, Virdi PS. Fundus lesions in malignant hypertension. VI. Hypertensive choroidopathy. Ophthalmology. 1986;93(11):1383-400.
  • 20. Prado RS, Figueiredo EL, Magalhaes TV. Retinal detachment in preeclampsia. Arq Bras Cardiol. 2002;79(2):183-6.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: 4
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
Sayıdaki Diğer Makaleler

Turkish Reliability of National Institutes of Health (NIH) patient-reported outcomes measurement information system (PROMIS®) Gas/Bloating Scale

Ahmet MAMUR, MEHMET KAYHAN, UĞUR BİLGE, Serkan SUNGUR, Hüseyin BALCIOĞLU, İlhami ÜNLÜOĞLU

Caveolin-1 gene expression in rats model of chronic renal failure

Berna ÖZYAZGAN, Müslüm AKGÖZ, Yılmaz ÇİĞREMİŞ

The role of hyponatremia in preeclampsia

Erdinç SARIDOĞAN, Ayşe KIRBAŞ, Burak ELMAS, Turhan ÇAĞLAR

The importance of procalcitonin in early diagnosis of sepsis

Funda YETKİN, Sibel Altunisik TOPLU

Ischemic stroke in young age?

Güleser AKPINAR, Harika GUNDUZ, Mehmet SERİN, Adem MELEKOGLU

Managemet of puerperal vulvovaginal hematoma with different suture technique; case report

Ahmet ESER, Ahter Tanay TAYYAR, Gulhan SAGİROGLU, Çetin KILIÇÇI, Cigdem Abide YAYLA, İlter YENİDEDE

Adipocytokine levels in benign prostate hyperplasia and prostate cancer patients

GÖKHAN TEMELTAŞ, FUNDA KOSOVA, TALHA MÜEZZİNOĞLU, Zeki ARI

Comparison of diffusion-weighed MRI findings of the testis in patients with the advanced stage unilateral testicular varicocele

Veysel BURULDAY, MEHMET HAMDİ ŞAHAN, Gülnur ERDEM, Ercan YUVANÇ

Neuromyelitis optica spectrum disorder: a pediatric case report

Müjgan ARSLAN, Serdal GÜNGÖR, Betül KILIÇ, Kader Karlı OĞUZ

The importance of morel-lavallee lesion in medicolegal evaluation: a case report

Ahsen KAYA, Muhammed Emin GOKSEN, Ugur ATA, Ekin Özgür AKTAŞ