Melih AKYOL, Rukiye Yasak GÜNER, Yusuf Cihan DİRİM, Mustafa TOSUN, İsmail TURGUT

Evaluation of cardiovascular risk in people with rosacea: A prospective study

Systemic inflammation is accepted as a nontraditional cardiovascular risk factor and has been shown to play a role in all stages of atherosclerosis. Rosacea is a chronic inflammatory skin disease. In our study, we aimed to evaluate the cardiovascular risk in rosacea patients. 40 people with rosacea (30 women, 10 men) and a control group of 40 age- and sex-matched individuals (28 women, 12 men) who had no chronic inflammatory skin disease were included in the study. Participants' body mass index (BMI) was calculated and their blood pressure was measured. Fasting blood glucose, fasting blood insulin, lipid profile, hemogram, basic biochemical parameters, erythrocyte sedimentation rate, and C-reactive protein levels were analyzed after at least 8 hours of fasting. In all participants, carotid intima-media thickness (CIMT) was measured using high-resolution B-mode ultrasonography (with a 4 MHz linear transducer. The mean CIMT values were 0.62 (0.18) mm in the rosacea group and 0.50 (0.14) mm in the control group. Statistical comparison indicated that mean CIMT was significantly greater in the patients with rosacea compared to the control group (p=0.001). There was no significant difference between the rosacea and control groups in terms of mean height, weight, BMI, or systolic and diastolic blood pressures (p>0.05). People with rosacea should be monitored periodically in terms of cardiovascular disease risk.

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