Although percutaneous transcatheter atrial septal defect (ASD) closure (TCC) has been performed on adults for a long time there is limited data about the effects of the procedure in the literature and the majority of studies have been performed on children. The study purposed to evaluate the impact of TCC on cardiac remodeling, electrical changes and exercise capacity in adults. Transthoracic echocardiography and electrocardiography were performed one day before and six months after TCC in 27 consecutive patients who underwent successful TCC. Twenty-seven age and sex matched healthy subjects were used as control group. Right ventricular (RV) diameter (had decreased from 44±6.3 to 34±3.9; p
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1. Fischer G, Stieh J, Uebing A, Hoffmann U, Morf G, Kramer HH. Experience with transcatheter closure of secundum atrial septal defects using the Amplatzer septal occluder: a single centre study in 236 consecutive patients. Heart. 2003;89(2):199-204.
2. Pascotto M, Santoro G, Cerrato F, Caputo S, Bigazzi MC, Iacono C, Carrozza M, Russo MG, Caianiello G, Calabro` R. Time course of cardiac remodeling following transcatheter closure of atrial septal defect. Int J Cardiol. 2006;112(3):348-52.
3. Du ZD, Hijazi ZM, Kleinman CS, Silverman NH, Larntz K. Comparison between transcatheter and surgical closure of secundum atrial septal defects in children and adults: results of a multicenter nonrandomized trial. J Am Coll Cardiol. 2002; 39(11):1836-44.
4. Thilen U, Persson S. Closure of atrial septal defect in the adult. Cardiac remodeling is an early event. Int J Cardiol. 2006;108(3):370- 5.
5. Podnar T, Martanovic P, Gavora P, Masura J. Morphological variations of secundum-type atrial septal defects: feasibility for percutaneous closure using Amplatzer septal occluders. Catheter Cardiovasc Interv. 2001;53(3):386-91.
6. Veldtman GR, Razack V, Siu S, El-Hajj H, Walker F, Webb GD, Benson LN, McLaughlin PR. Right ventricular form and function after percutaneous atrial septal defect device closure. J Am Coll Cardiol. 2001;37(8):2108-13.
7. Guray U, Guray Y, Yilmaz MB, Mecit B, Sasmaz H, Korknaz S,Kutuk E. Evaluation of P-wave duration and P-wave dispersion in adult patients with secundum atrial septal defect during normal sinus rhythm. Int J Cardiol. 2003;91(1):75-9.
8. Gatzoulis MA, Redington AN, Somerville JS, Shore DF. Should atrial septal defects be closed in adults. Ann Thorac Surg. 1996;61(2):657-9.
9. Kaya MG, Baykan A, Dogan A, Inanc T, Gunebakmaz O, Dogdu O, Uzum K, Eryol NK, Narin N. Intermediate-term effects of transcatheter secundum atrial septal defect closure on cardiac remodeling in children and adults. Pediatr Cardiol. 2010;31(4):474- 82.
10. Monfredi O, Luckie M, Mirjafari H, Willard T, Buckley H, Griffiths L, Clarke B, Mahadevan VS. Percutaneous device closure of atrial septal defect results in very early and sustained changes of right and left heart function. Int J Cardiol. 2013;167(4):1578-84.
11. Meyer RA, Korfhagen JC, Covitz W, Kaplan S. Long-term follow-up study after closure of secundum atrial septal defect in children: an echocardiographic study. Am J Cardiol. 1982;50(1):143-8.
12. Giardini A, Donti A, Specchia S, Formigari R, Oppido G, Picchio FM. Long-term impact of transcatheter atrial septal defect closure in adults on cardiac function and exercise capacity. Int J Cardiol. 2008;124(2):179-82.
13. Fang F, Luo XX, Lin QS, Kwong JS, Zhang YC, Jiang X, Yu CM, Lam YY. Characterization of mid-term atrial geometrical and electrical remodeling following device closure of atrial septal defects in adults. Int J Cardiol. 2013;168(1):467-71.
14. Kort HW, Balzer DT, Johnson MC. Resolution of Right Heart Enlargement After Closure of Secundum Atrial Septal Defect With Transcatheter Technique. J Am Coll Cardiol. 2001;38(5):1528-32.
15. Brandenburg RO, Holmes DR, Brandenburg RO, Mc Goon DC. Clinical follow-up study of paroxysmal supraventricular tachyarrhythmias after operative repair of secundum type atrial septal defect in adults. Am J Cardiol. 1983;51(2):273-6.
16. Spargias KS, Lindsay SJ, Kawar GI, Greenwood DC, Cowan JC, Ball SG, Hall AS. QT dispersion as a predictor of longterm mortality in patients with acute myocardial infarction and clinical evidence of heart failure. Eur Heart. J 1999;20(16):1158-65.
17. Santoro G, Pascotto M, Caputo S, Gaio G, Iacono C, Caso I, Sarubbi B, Carrozza M, Russo MG, Calabrò R. Early electrical and geometric changes after percutaneous closure of large atrial septal defect. Am J Cardiol. 2004;93(7):876-80.