Faruk İNCECİK, YUSUF ÖNLEN, Cahit ÖZER, Kenan ÖZCAN

Metoclopramide induced acute dystonic reaction: Two case reports

Metoklopramid, çocukluk çağında yaygın olarak kullanılan antiemetik bir ajan olup, en sık görülen yan etkisi ekstrapiramidal reaksiyonlardır. Çocuklarda insidansı % 0.5-1 iken, adölesan ve yaşlılarda % 25 civarındadır. Hastalar, meninjit, ensefalit, hipokalsemi, nöbet ve tetanoz şeklinde yanlış tanı alabilmektedir. Biz de ensefalit ön tanısı ile hastanemize sevk edilen 8 aylık ve 10 yaşında iki erkek hastada, metoklopramide bağlı akut distonik reaksiyon gelişen iki vaka saptadık.

Metoklopramide bağlı akut distonik reaksiyon: İki olgu sunumu

Metoclopramide is a widely used antiemetic agent in paediatric population with the primary side-effect of extrapyramidal reactions. Incidence is 0.5-1% in children while incidence in young adults and elders is 25%. Patients can be misdiagnosed as meningitis, encephalitis, hypocalcemia, seizure and tetanus. We report two cases, 8-month-and 10-year-old boys referred to our hospital with a presumptive diagnosis of encephalitis and diagnosed as metoclopramide induced acute dystonic reaction, to stress this side-effect of metoclopramide.

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