Büşra FENDOĞLU, KURUÜZÜM Ayşe UZ, Didem ŞÖHRETOĞLU

Mantarlardan Elde Edilen Alkaloitler

Mantarlar (makrofunguslar) besin kaynağı ve ilaç olarak özellikle Doğu Asya’da yüzyıllardır diyetin bir parçasıdır. Son zamanlarda üzerlerinde yapılan çalışmaların sayısının artması nedeniyle mantarların ve ekstrelerinin tıbbi amaçla kullanımı daha popüler hale gelmiştir. Mantarlar çoğunlukla polisakkaritler, terpenler ve steroller taşımaktadır. Alkaloitler çok düşük dozlarda bile biyoaktif etki gösterirler ve genellikle Angiospermlerde bulunurlar. Bu grup bileşiklerin makrofunguslarda bulunuşları oldukça sınırlıdır ve haklarında polisakkaritler ya da terpenler gibi diğer bileşiklerin mantarlarda yayılışları kadar detaylı bilgi yoktur. Bu derlemede, mantarlarda bulunan alkaloitlerin dağılımı ve biyoaktivitelerine odaklandık.

Anahtar Kelimeler:

makrofungus, alkaloit, Mycena, psilosibin, erinaserin, piriferin

Alkaloids from Mushrooms

Mushrooms (macrofungi) are a part of the human diet as a source of both food and medicine for centuries especially in East-Asia. The use of mushrooms and their extracts for medicinal purposes became more popular due to increasing number of research conducting on them recently. They predominantly contain polysaccharides, terpenes and sterols. Alkaloids exhibits bioactive effects even in very small doses and mainly distributed in Angiosperms. Their occurrences in macrofungi is very limited and not very-well documented as much as other constituents like polysaccharides or terpenes. In this review, we focused on distribution and bioactivities of mushroom alkaloids.

Keywords:

macrofungi, alkaloid, Mycena, psilocybin, erinacerin, pyriferine,

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ISSN: 2147-6845
Yayın Aralığı: Yılda 2 Sayı
Başlangıç: 2010
Yayıncı: Selçuk Üniversitesi Mantarcılık Uygulama ve Araştırma Merkezi Müdürlüğü