Ayşe Naciye Erbakan, Aytekin Oğuz, Mirac Vural Keskinler, Esen Ertur, İrem Bozkurt Çakır

TİP 2 DİYABETLİ HASTALARDA DİYABETİK PERİFERİK NÖROPATİ SIKLIĞI, İLİŞKİLİ FAKTÖRLER VE FARKINDALIK DURUMUNUN DEĞERLENDİRİLMESİ

Amaç: Diyabetik nöropati sıklıkla hastanın şikayeti olursa veya önlenebilecek komplikasyonlar gelişmişse tanı almaktadır. Tip 2 diyabetli (T2DM)hastalarda diyabetik periferik nöropati (DPN) varlığının bildirildiğinden daha sık olduğu hipotezinden yola çıkarak bu hasta grubunda DPN sıklığınıve ilişkili olduğu durumları araştırmayı planladık.Yöntem: Diyabet polikliniklerimize başvuran 336 tip 2 diyabetli hasta çalışmaya alındı. Anamnezleri, demografik ve antropometrik bilgileri,kullandıkları ilaçlar ve laboratuvar verileri kaydedildi. Diyabetik nöropatiyi saptamak amacıyla MNSI (Michigan Neuropathy Screening Instrument)skorlaması ve Semmes-Weinstein monofilaman testi uygulandı.Bulgular: Bu 336 hastanın (yaş ortalaması 57,9±10 yıl, %63,7’si kadın) ortalama diyabet süresi 9,5±7,8 yıldı. HbA1c, açlık kan şekeri ve vücutkütle indeksi ortalaması sırasıyla %8,7±2, 182±89 mg/dl ve 32±5,8 kg/m2bulundu. DPN sıklığı %38,7 (n=130) saptandı. Daha önce nöropatitedavisi başlanmış olan 32 hasta (%9.5) ilaç kullanımları nedeniyle diğer analizlere katılmadı. Diyabetik nöropatisi olan grupla (n=107) olmayangrup (n=197) arasında kadın cinsiyet (%71 vs %59,9, p=0,054), yaş (60,6 yıl vs 55,9 yıl, p

THE EVALUATION OF PERIPHERAL DIABETIC NEUROPATHY; FREQUENCY, ASSOCIATED FACTORS AND AWARENESS IN PATIENTS WITH TYPE 2 DIABETES

Objective: Diabetic neuropathy is often diagnosed only if the patient complains or after the development of complications. We hypothesized that diabetic peripheral neuropathy (DPN) is more common than reported and aimed to investigate the incidence and related conditions of DPN in type 2 diabetic (T2DM) patients. Methods: Three hundred and thirty six patients with type 2 diabetes who presented to our diabetes outpatient clinics were recruited. Patients’ history, demographic and anthropometric characteristics, medications and laboratory data were recorded. MNSI (Michigan Neuropathy Screening Instrument) and Semmes-Weinstein monofilament test were applied to detect diabetic neuropathy. Results: In the 336 patients (mean age, 57.9±10 years; 63.7% female), the mean duration of diabetes was 9.5±7.8 years. The mean HbA1c and fasting blood glucose (FBG) concentrations, and body mass index (BMI) were 8.7±2%, 182±89 mg/dL and 32±5.8 kg/m2 , respectively. The incidence of DPN was 38.7% (n=130). Female gender (71% vs 59.9%, p=0.054), age (60.6 years vs 55.9 years, p

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