Obsesif Kompulsif Bozuklukta bilişsel işlevlerin Adas-Cog ölçeği ile değerlendirilmesi: Sağlıklı kontrol grubuyla karşılaştyrmalı bir çalyşma

Amaç: Obsesif Kompulsif Bozukluk (OKB) yineleyici vesürekli dü?ünceler ile tekrarlanan davrany?larla karakterizedir. Önceki çaly?malarda OKB hastalarynda bellek vedi?er nörokognitif i?levlerde sorunlaryn oldu?u saptanmy?tyr. Çaly?mamyzdaki amacymyz OKB hastalaryndaki bili?sel i?lev bozukluklaryny Alzheimer hastalarynda kullanylan Alzheimer Hastaly?y De?erlendirme ölçe?i-Bili?selAlt ölçe?i (Adas-Cog) ile belirlemeye çaly?maktyr. Gereçve Yöntem: Çaly?maya DSM-IV tany ölçütlerine göre OKBtanysy alan 32 hasta ile 26 sa?lykly kontrol alynmy?tyr.Olgulara Yale-Brown Obsesyon-Kompulsiyon Ölçe?i (YBOKÖ), Yapylandyrylmy? Klinik Görü?me (SCID-I), ADAScog ve Mini Mental Durum Yncelemesi Testi (MMDM),Depresyon ve anksiyete ?iddetini belirlemek içinHamilton Depresyon De?erlendirme Ölçe?i (HDDÖ) veHamilton Anksiyete De?erlendirme (HADÖ) ölçekleriuygulanmy?tyr. Bulgular: ADAS-Cog toplam ve alt maddeskorlary iki grup arasynda kar?yla?tyryldy?ynda, ADAS-COGtoplam (p

Evaluation of neurocognitive deficits in obsessive compulsive disorder with Adas-cog: A comparative study with the healthy control group

Objective: Obsessive compulsive disorder (OCD) is characterized by recurrent intrusive thoughts and repetitivebehaviors or mental acts compulsions. Previous studiesobviously indicate that OCD patients have several impairments in memory and other neurocognitive functions.Our primary aim is to assess the cognitive impairment inOCD patients through Alzheimer's Disease AssessmentScale Cognitive Subscale (ADAS-Cog) which is widelyused in Alzheimer's Dementia. Method: Thirty twopatients with a diagnosis of OCD and twenty six healthycontrols were administrated Structured Clinical Interviewfor DSM Disorders (SCID-I), Yale Brown ObsessiveCompulsive Scale (Y-BOKS), ADAS-Cog Scale, MiniMental Status Examination (MMSE), HamiltonDepression Rating Scale (HDRS) and Hamilton AnxietyRating Scales (HARS). Results: When we compared twogroups, OCD subjects performed significantly worse inthe fields of ADAS-Cog Total (p<0.0001), Word Recall(p<0.0001), Word Recognition (p<0.0001) Commands(p<0.0001), Constructional Praxis (p<0.05) andOrientation (p<0.05) Tests of ADAS-Cog compared tothe healthy control group. Conclusion: We suggest thatADAS-Cog might be used as an available tool to assesssome neurocognitive deficits in OCD patients. Furtherstudies in larger samples of OCD patients are needed toassess the availability of ADAS-Cog in measuring theneurocognitive impairments

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