Shahab BAHADORAN, Hossein HASSANPOUR, Khodadad Pirali KHEIRABADI, Sepehr SHEKARCHIAN

Effect of Clopidol and Amprolium/Ethopabate on performance and intestinal morphology of chickens with experimental coccidiosis

İki antikoksidial ilacın deneysel koksidiyaziste büyüme performansı ve barsak mukozasına etkilerini araştırmak amacıyla broiler civcivlere Eimeria oositleri/Clopidol ve Amprolium + Ethopabate verildi. Bu uygulamaların yapıldığı tavuklarda büyüme performansının negatif olarak etkilendiği belirlendi. Barsağın çoğu morfometrik parametrelerinin uygulama gruplarında negatif kontrole oranla azaldığı tespit edildi (P

Deneysel koksidiyozlu Tavuklarda Clopidol ve Amprolium/Ethopabate uygulamasının performans ve barsak morfolojisine etkisi

To investigate effects of two anticoccidial drugs on growth performance and intestinal mucosa in experimental coccidiosis, broiler chicks challenged/medicated by oocytes of Eimeria/Clopidol and Amprolium + Ethopabate. There were negative effects on growth performance in chickens infected/medicated by these drugs. Most morphometric parameters of intestine were decreased in infected or medicated groups compared to negative control (P<0.05). Duodenal villus height in infected/unmedicated group and villus surface area in all infected groups were lowest between infected or medicated groups (P<0.05). Duodenal villus width was also decreased in all medicated groups compared to negative control, but this decreasing was only significant in infected / medicated groups. Jejunal villus height, width and surface area in infected/unmedicated group were lowest as compared to other uninfected / medicated groups (P<0.05). Ileal villus height in infected/unmedicated group were lowest as compared to all medicated groups. In infected/medicated groups, ileal villus surface area was significantly lower than uninfected/medicated groups. There were no significant differences between Clopidol- and Amprolium + Ethopabate-medicated groups in intestinal morphometric assessment. It is concluded that Clopidol and Amprolium + Ethopabate have adverse effects on chicken performance and intestinal morphology especially villus dimensions and absorptive surface during control or prevention of coccidiosis.

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