Peptik ülser hastalarında sempatik sinir sisteminin elektrofizyolojik olarak değerlendirilmesi

AMAÇ: Bu çalıșmanın amacı sempatik deri testi bulgularının helikobakter pilori testleri pozitif ve negatif olan hastalarda karșılaștırmaktır. YÖNTEM: Helikobakter pilori pozitif 20 peptik ülser hastası (1. grup), helikobakter pilori negatif 20 peptik ülser hastası (2. grup) ve 20 sağıklı kontrol grubu katılımcısına sempatik cilt testi çalıșıldı. Üç gruba da test uygulandı, amplitüd ve latanslar ölçüldü. Test bulgularına göre BULGULAR: Grup 1, Grup 2 ve kontrol grubu katılımcılarınıntalama yașları sırasıyla 48,7, 46,5 ve 46,3’tü. Her üç grup arasın- da yaș ve cinsiyet açısından anlamlı fark yoktu. Latans değerleri 1. Grupta 1,44±0,3; 2. Grupta 1,49±0,15; 3. Grupta ise 1,54±0,1 ms idi. Amplitüd değerleri 1. Grupta 935±258; 2. Grupta 949±320 iken, sağlıklı kontrollerde 895±360 μV idi. Amplitüd ve latans değerlerinde üç grup arasında anlamlı farklılık yoktu. SONUÇ: Helikobakter pilori pozitif ve negatif olan peptik ülser hastalarında sempatik deri yanıtlarının amplitüd ve latans değerleri sağlıklı kontrollerin sonuçları ile benzerdir.

The electrophysiological evaluation of sympathetic nervous system in patients with peptic ulcer

AIM: The aim of the study was to compare the results of sympathetic skin test in patients with positive and negative test results for helicobacter pylori. METHODS: Sympathetic skin response was studied in helicobacter pylori positive 20 peptic ulcer patients (Group 1), helicobacter pylori negative 20 peptic ulcer patients (Group 2) and 20 healthy controls (Group 3). Sympathetic skin response test applied in all three groups, amplitudes and latencies were recorded. Three groups were compared with the test results. RESULTS: The mean ages of the participants of Group 1, Group 2 and control group were 48.7, 46.5 and 46.3 years, respectively. The mean age and the female/male ratio did not differ significantly among the groups. The mean sympathetic skin response latency was 1.44±0.3 in Group 1; 1.49±0.15 in Group 2 and 1.54±0.1 ms in controls. The mean amplitude values were 935±258 in Group 1; 949±320 in Group 2 and 895±360 μV in controls. There were no significant differences in terms of latency and amplitude among the three groups. CONCLUSION: Latency and amplitude values of the sympathetic skin response are similar in helicobacter pylori positive and negaive peptic ulcer patients and healthy controls.

Kaynakça

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