Spermatocytic Seminoma with Sarcomatous Transformation: The First Brazilian Case Report

The cases of spermatocytic seminoma with sarcomatoid transformation are rare. When there is sarcomatoid transformation, the tumor takes an aggressive pattern, with high rates of metastasis and a worse prognosis. We present the case of a 42-year-old man with a slow enlargement of the left testicle over more than 18 months, which progressed to a pronounced and painful growth in the last six months. Computed tomography showed a left retroperitoneal mass in the renal area affecting the stomach. Total orchiectomy with partial scrotectomy was performed in the left testicle and the patient was referred to the oncology department for chemotherapy.

Sarkomatöz Dönüşüm ile Spermatositik Seminom: Brezilya’ya Özgü İlk Olgu Sunumu

Sarkomatöz dönüşüm gösteren spermatositik seminom olguları nadirdir. Sarkomatöz dönüşüm olduğunda, tümör yüksek oranda metastaz ve daha kötü bir prognoz şeklinde agresif bir yol izler. On sekiz aydan fazla bir süredir sol testiste yavaş bir büyüme olan, son altı ayda ise bu büyüme belirgin ve ağrılı bir hale gelen, 42 yaşında bir erkek hastayı sunuyoruz. Bilgisayarlı tomografi, renal bölgede mideye etki eden sol retroperitoneal kitleyi gösterdi. Sol testiste parsiyel skrotektomi ile total orşiektomi yapıldı ve hasta kemoterapiye yönlendirildi.

Kaynakça

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Cabral-Ribeiro J, Santos A, Mendes V, Sousa L, Monteiro P, Rodrigues J. Seminoma espermatocítico: Caso Clínico. Acta Urológica Portuguesa 2000;17:85-88.

Menon S, Karpate A, Desai S. Spermatocytic seminoma with rhabdomyosarcomatous differentiation: A case report with a review of the literature. J Can Res Ther 2009;5:213-215

Stueck AE, Grantmyre JE, Wood LA, Wang C, Merrimen J. Spermatocytic Tumor With Sarcoma: A Rare Testicular Neoplasm. Int J Surg Pathol 2017;25:559-562.

Chung PW, Bayley AJ, Sweet J, Jewett MA, Tew-George B, Gospodarowicz MK, Warde PR. Spermatocytic seminoma: a review. Eur Urol 2004;45:495- 498.

Wetherell D, Lawrentschuk N, Gyomber D. Spermatocytic seminoma with sarcoma: an indication for adjuvant chemotherapy in localized disease. Korean J Urol 2013;54:884-887.

Trivedi P, Pasricha S, Gupta A. Spermatocytic seminoma associated with undifferentiated sarcoma: A rare case report. Indian J Pathol Microbiol 2011;54:138-140.

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