Multifocal Synchronous Chromophobe, Papillary, and Clear Cell Renal Cell Carcinoma in a Single Kidney

We present a unique case of concurrent chromophobe, clear cell, and papillary renal cell carcinomas (RCC) in three separate sites in the same kidney after partial nephrectomy. We review the literature of synchronous RCC of up to two histologic subtypes, which is rare in occurrence.

Tek Bir Böbrekte Çok Odaklı Eş Zamanlı Kromofob, Papiller ve Berrak Hücreli Tipte Renal Hücreli Karsinom

Bu çalışmada, parsiyel nefrektomi sonrası aynı böbreğin üç ayrı bölgesinde eş zamanlı kromofob, berrak hücreli ve papiller renal hücreli karsinomu (RHK) olan eşsiz bir olgu sunulmuştur. Eş zamanlı iki histolojik alt tip bile oldukça nadir görülmektedir. Literatür eşliğinde eş zamanlı çoklu alt tip RHK gözden geçirilmiştir.

Kaynakça

Petrolla AA, MacLennan GT. Renal cell carcinoma and other concurrent renal neoplasms. J Urol 2007;178:2163.

Morelli L, Pusiol T, Piscioli I, Larosa M, Pozzoli GL, Monica B. Concurrent occurrence of three primary neoplasms with different hystotype in the same kidney, associated with an adenoma of the omolateral adrenal gland: first case report. Int J Urol 2006;13:1236-1239.

Na KY, Kim HS, Park YK, Chang SG, Kim YW. Multifocal renal cell carcinoma of different histological subtypes in autosomal dominant polycystic kidney disease. Korean J Pathol 2012;46:382-386.

Tyritzis SI, Alexandrou PT, Migdalis V, Koritsiadis G, Anastasiou I. Synchronous chromophobe and papillary renal cell carcinoma. First report and review of the pathogenesis theories. Pathol Int 2009;59:193-196.

Roehrl MH, Selig MK, Nielsen GP, Dal Cin P, Oliva E. A renal cell carcinoma with components of both chromophobe and papillary carcinoma. Virchows Arch 2007;450:93-101.

Jun SY, Cho KJ, Kim CS, Ayala AG, Ro JY. Triple synchronous neoplasms in one kidney: report of a case and review of the literature. Ann Diagn Pathol 2003;7:374-380.

Kang SG, Ko YH, Kang SH, Kim J, Kim CH, Park HS, Moon du G, Lee JG, Kim JJ, Cheon J. Two different renal cell carcinomas and multiple angiomyolipomas in a patient with tuberous sclerosis. Korean J Urol 2010;51:729-732.

Kaynak Göster

  • ISSN: 2148-9580
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2014

2.1b 1.5b

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