Interpreting a Radical Prostatectomy Report

Worldwide, clinically detected prostate cancer is the second most common malignancy, with an estimated 1.1 million new cases in 2012. Standard active treatments for prostate cancer include radiotherapy and/or radical prostatectomy (RP) (for clinically localized prostate cancer). Also active surveillance is a management strategy to avoid or delay the potential harms caused by radical treatments. At this point, a pathology report plays a major role. Appropriate handling and systematic examination of a RP specimen is essential for the identification of tumor characteristics such as grade, volume, pathological stage, and surgical margin status. Although some minor differences in macroscobic evaluation may be seen among authors, it is essential to paint and sample the entire prostatectomy specimen. Most prostate tumors are heterogeneous and multifocal compared to tumors of other organs. This makes macroscopic assessment of prostatectomy specimen challenging and sampling of a representative material from the main tumor focus difficult. Also determining tumor burden and to interpret all surgical margins total sampling of the material is essential.

Radikal Prostatektomi Raporunun Yorumlanması

Dünyada, klinik olarak tespit edilen prostat kanseri, 2012’de tahmin edilen 1,1 milyon yeni olguyla en sık görülen ikinci malignitedir. Prostat kanseri için standart aktif tedaviler arasında radyoterapi ve/veya radikal prostatektomi (klinik olarak lokalize prostat kanseri için) bulunur. Ayrıca aktif izlem, diğer tedavilerin neden olduğu olası zararları önlemek veya geciktirmek için uygun hastalarda alternatif bir tedavi yöntemidir. Bu noktada patoloji raporu önemli rol oynar. Radikal prostatektomi materyalinin uygun makroskobik incelemesi ve örneklenmesi son derece önemlidir. Otörler arasında bazı küçük farklılıklar görünse de, prostatektomi materyalini boyamak ve total örneklemek gerekir. Ayrıca tümör yükünün belirlenmesi ve tüm cerrahi sınırların yorumlanabilmesi için totale yakın örnekleme önemlidir.

Kaynakça

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Kaynak Göster

  • ISSN: 2148-9580
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2014

2.5b 1.7b

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