Development of Antibiotic Resistance Against Ureaplasma urealyticum Strains Isolated from Urogenital Samples

Objective: To assess any change in the antibiotic sensitivity of Ureaplasma urealyticum strains isolated from urogenital samples in the course of time. Materials and Methods: Hospital records were retrospectively examined and cases with growth of U. urealyticum in urogenital samples in the years 2008 and 2013 were identified. Furthermore, the change in the course of time was examined by taking into consideration the cases we reported in 2001. Results: Higher rates of sensitivity against tetracycline and doxycycline were observed in 60 patients with isolated U. urealyticum. Higher rates of resistance against ofloxacin and ciprofloxacin were observed. A significant difference was found in resistance against antibiotics when the records of 2008 and 2013 were compared. A statistically significant increase was found in resistance against ofloxacin and ciprofloxacin when the records of 2001 were compared with the records of 2008 and 2013 (p

Ürogenital Örneklerden İzole Edilen Ureaplasma urealyticum Suşlarına Karşı Antibiyotik Direnç Gelişimi

Amaç: Ürogenital örneklerden izole edilen Ureaplasma urealyticum suşlarının antibiyotiklere karşı duyarlılıklarının zaman içerisinde değişip değişmediğinin değerlendirilmesidir. Gereç ve Yöntem: Hastane kayıtları retrospektif olarak incelenerek 2008 ve 2013 yılları içerisinde ürogenital örneklerde U. urealyticum üreyen olgular belirlenmiştir. Ayrıca 2001 yılında tebliğ ettiğimiz olgular göz önünde bulundurularak zaman içerisindeki değişim incelenmiştir. Bulgular: U. urealyticum izole edilen 60 hastada tetrasiklin ve doksisikline karşı yüksek oranlarda duyarlılık gözlenmiştir. Ofloksasin ve siprofloksasine karşı direncin yüksek oranlarda olduğu gözlenmiştir. 2008 ve 2013 yılları karşılaştırıldığında antibiyotiklere karşı direnç oranlarında anlamlı bir farklılık gözlenmemiştir. 2001 yılı kayıtları 2008 ve 2013 yılları kayıtları ile karşılaştırıldığında ofloksasin ve siprofloksasine karşı direncin istatistiksel olarak anlamlı bir şekilde arttığı gözlenmiştir (p

Kaynakça

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