An Extremely Rare Kidney Tumor: Primary Intraparenchymal Squamous Cell Carcinoma

Primer renal parankimal renal skuamöz hücreli karsinom oldukça nadir bir patoloji olup, bugüne değin literatürde sadece 4 olgu bildirilmiştir. Yetmiş üç yaşında kadın hasta kliniğimize sağ flank ağrısı şikayetiyle başvurdu. Radyolojik incelemede sağ böbrek üst polünde 6x5x4 cm boyutunda heterojen kontrastlanma gösteren hipodens kitle saptandı. Hastaya laparoskopik nefrektomi uygulandı ve patolojik incelemede tanının skuamoz hücreli karsinom olduğu görüldü. Hastaya metastaz araştırması için çekilen postoperatif pozitron emisyon tomografisi/bilgisayarlı tomografide herhangi bir patolojik tutulum görülmedi. Hastamız halen sağlıklıdır ve herhangi bir adjuvan tedavi almamıştır

Oldukça Nadir Bir Böbrek Tümörü: Primer İntraparankimal Skuamöz Hücreli Karsinom

Primary squamous cell carcinoma of the renal parenchyma is a rare entity and only 4 cases have been reported in the literature. A 73-year-old female patient presented to our clinic with the complaint of right flank pain. On radiologic evaluation, a 6x5x4 cm hypodense mass showing heterogeneous contrast enhancement was observed in the upper pole of the right kidney. An uneventful laparoscopic radical nephrectomy was performed. Final pathologic diagnosis was squamous cell carcinoma. No pathological involvement was observed on postoperative positron emission tomography/computed tomography. Our patient is still alive and she has not received any adjuvant treatment

Kaynakça

1. Jain A, Mittal D, Jindal A, Solanki R, Khatri S, Parikh A, Yadav K. Incidentally detected squamous cell carcinoma of renal pelvis in patients with staghorn calculi: case series with review of the literature. ISRN Oncol 2011;2011:620574.

2. Ghosh P, Saha K. Primary intraparenchymal squamous cell carcinoma of the kidney: a rare and unique entity. Case Rep Pathol 2014;2014:256813.

3. Terada T. Synchronous squamous cell carcinoma of the kidney, squamous cell carcinoma of the ureter and sarcomatoid carcinoma of the urinary bladder: a case report. Pathol Res Pract 2010;206:379-383.

4. Kulshreshtha P, Kannan N, Bhardwaj R, Batra S. Primary squamous cell carcinoma of the renal parenchyma. Indian J Pathol Microbiol 2012;55:370- 371.

5. Wang Z, Yan B, Wei YB, Hu NA, Shen Q, Li D, Yang JR, Yang X. Primary kidney parenchyma squamous cell carcinoma mimicking xanthogranulomatous pyelonephritis: A case report. Oncol Lett 2016;11:2179-2181.

6. Bandyopadhyay R, Biswas S, Nag D, Ghosh AK. Squamous cell carcinoma of the renal pelvis presenting as hydronephrosis. J Cancer Res Ther 2010;6:537- 539.

7. Bonsib SM, Cheng L. Renal pelvis and ureter. In: Cheng L, Bostwick DG. Urologic Surgical Pathology. 2nd ed. Philadelphia, Saunders&Elsevier, 2008, pp. 173-193.

8. Lopez-Beltran A, Montironi R, Vidal-Jimenez A, Cheng L. Pathology of tumors of the urinary bladder. In: Mikuz G. Clinical Pathology of Urologic Tumors. Florida, Informa Healthcare, 2007, pp. 57-89.

9. Maclennan GT, Cheng L. Renal pelvis and ureter. In: Maclennan GT, Cheng L. Atlas of Genitourinary Pathology. New York, Springer, 2011, pp. 123-140.

10. Bhaijee F. Squamous cell carcinoma of the renal pelvis. Ann Diagn Pathol 2012;16:124-127.

11. Dell’Aprovitola N, Guarino S, Del Vecchio W, Camera L, Chiancone F, Imbimbo C, Salvatore M, Imbriaco M. Xanthogranulomatous pyelonephritis mimicking a renal cell carcinoma: a unique and challenging case. Acta Radiol Short Rep 2014;3:2047981613513763.

12. Kato N, Yasukawa K, Onozuka T, Kimura K. Paraneoplastic syndromes of leukocytosis, thrombocytosis, and hypercalcemia associated with squamous cell carcinoma. J Dermatol 1999;26:352-358.

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