Hacer ALATAŞ, Nurgül ARSLAN, İrem PEMBEGÜL

The relationship of dietary antioxidant capacity with laboratory and anthropometric measurements in hemodialysis patients

Anahtar Kelimeler:

Hemodialysis, diet total antioxidant capacity, anthropometric parameters, Hemodialysis, diet total antioxidant capacity, anthropometric parameters

The relationship of dietary antioxidant capacity with laboratory and anthropometric measurements in hemodialysis patients

Aim: Dietary antioxidant intake correlates with blood antioxidant content and protects against oxidative damage and related inflammatory complications. This study was conducted to examine the relationship between total antioxidant capacity of diet and effective factors with laboratory and anthropometric parameters in patients undergoing hemodialysis. Material and Method: The present case-control study consisted of 62 cases and 59 controls individuals who received hemodialysis treatment between the ages of 35-75. Dietary intake, sociodemographic data, medical history, and anthropometric measurements were collected from participants using a validated questionnaire. Results: Examining the association between dietary components and diet's total antioxidant capacity (dTAC) reveals a positive correlation between dietary protein (kg/avg), beta carotene (mcg/day), vitamin C (mg/day), vitamin E (mg/day), and polyunsaturated fatty acids (PUFA) (g/day) (p=0.002). The serum albumin, serum neutrophil to lymphocyte ratio and HDL-cholesterol have been reported to have a positive relationship with dTAC. And body mass ındex (BMI) and other anthropometric parameters were found to have a negative connection with dTAC (p=0.007). Conclusion: Total dietary antioxidant capacity is effective on anthropometric measurements and serum laboratory values. Increasing the antioxidant capacity of the diet in hemodialysis patients is important to prevent complications related to inflammation.

Keywords:

Hemodialysis, diet total antioxidant capacity, anthropometric parameters,

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Rahman T, Hosen I, Islam MT, Shekhar HU. Oxidative stress and human health. Adv Biosci Biotechnol 2012; 3: 997-1019.
Yaribeygi H, Farrokhi FR, Rezaee R, Sahebkar A. Oxidative stress induces renal failure: A review of possible molecular pathways. J Cell Biochem 2018; 119: 2990-8.
Spittle M, Hoenich NA, Handelman G, Adhikarla R, Homel P, Levin NW. Oxidative stress and inflammation in hemodialysis patients. Am J Kidney Dis 2001; 1408-13.
Danielski M, Ikizler TA, McMonagle E, et al. Linkage of hypoalbuminemia, inflammation, and oxidative stress in patients receiving maintenance hemodialysis therapy. Am J Kidney Dis 2003; 42: 286-94.
Uddin MJ, Kim EH, Hannan MA, Ha H. Pharmacotherapy against oxidative stress in chronic kidney disease: Promising small molecule natural products targeting Nrf2-HO-1 signaling. Antioxidants 2021; 10-258.
Sangeetha Lakshmi B, Harini Devi N, Suchitra M, Srinivasa Rao P, Siva Kumar V. Changes in the inflammatory and oxidative stress markers during a single hemodialysis session in patients with chronic kidney disease. Ren Fail 2018; 40: 534-40.
Rhee CM, Leung AM, Kovesdy CP, Lynch KE, Brent GA, Kalantar‐Zadeh K. Updates on the management of diabetes in dialysis patients. Semin Dial 2014; 27: 135-45
Asghari G, Yuzbashian E, Shahemi S, Gaeini Z, Mirmiran P, Azizi F. Dietary total antioxidant capacity and incidence of chronic kidney disease in subjects with dysglycemia: Tehran Lipid and Glucose Study. Eur J Nutr 2018; 57: 2377-85.
Ghorbaninejad P, Mohammadpour S, Djafari F, Tajik S, Shab-Bidar S. Dietary total antioxidant capacity and its association with renal function and progression of chronic kidney disease in older adults: a report from a developing country. Clin Nutr Res 2020; 9: 296.
Weir CB, Jan A. BMI classification percentile and cut off points. Europe PMC plus 2019.
Goodman E, Daniels SR, Morrison JA, Huang B, Dolan LM. Contrasting prevalence of and demographic disparities in the World Health Organization and National Cholesterol Education Program Adult Treatment Panel III definitions of metabolic syndrome among adolescents. J Pediatr 2004;145: 445-51.
Maassen A, Strupp C, Giagounidis A, et al. Validation and proposals for a refinement of the WHO 2008 classification of myelodysplastic syndromes without excess of blasts. Leuk Res 2013; 37: 64-70.
Ashwell M. Charts based on body mass index and waist-to-height ratio to assess the health risks of obesity: a review. Open Obes J 2011; 3: 78-84.
Haytowitz DB, Bhagwat S. USDA database for the oxygen radical absorbance capacity (ORAC) of selected foods, Release 2. 2010; 3: 10-48.
Dehne LI, Klemm C, Henseler G, Hermann-Kunz E. The German food code and nutrient data base (BLS II. 2). Eur J Epidemiol 1999; 15: 355-8.
Rico MG, Puchades M, Ramón RG, Saez G, Tormos MC, Miguel A. Effect of hemodialysis therapy on oxidative stress in patients with chronic renal failure. Nefrologia 2006; 26: 218-25.
Nguyen‐Khoa T, Massy ZA, De Bandt JP, et al. Oxidative stress and haemodialysis: role of inflammation and duration of dialysis treatment. Nephrol Dial Transplant 2001;16: 335-40.
Zeng X, Liu J, Tao S, Hong HG, Li Y, Fu P. Associations between socioeconomic status and chronic kidney disease: a meta-analysis. J Epidemiol Community Health 2018; 72: 270-9.
Gerasimoula K, Lefkothea L, Maria L, Victoria A, Paraskevi T, Maria P. Quality of life in hemodialysis patients. Mater sociomed 2015; 27: 305-9.
Afsar B. Sociodemographic, clinical, and laboratory parameters related with presence of regular toothbrushing in hemodialysis patients. Ren Fail 2013; 35: 179-84.
Karadag E, Kilic SP, Metin O. Relationship between fatigue and social support in hemodialysis patients. Nurs Health Sci 2013; 15: 164-71.
Stepniewska J, Golembiewska E, Dolegowska B, Domanski M, Ciechanowski K, Science P. Oxidative stress and antioxidative enzyme activities in chronic kidney disease and different types of renal replacement therapy. Curr Protein Pept Sci 2015; 16: 243-8.
Mekki K, Taleb W, Bouzidi N, Kaddous A, Bouchenak M. Effect of hemodialysis and peritoneal dialysis on redox status in chronic renal failure patients: a comparative study. Lipids Health Dis 2010; 9: 1-7.
Rendo-Urteaga T, Puchau B, Chueca M, et al. Total antioxidant capacity and oxidative stress after a 10-week dietary intervention program in obese children. Eur J Pediatr 2014; 173: 609-16.
Rajendran P, Nandakumar N, Rengarajan T, et al. Antioxidants and human diseases. Clin Chim Acta 2014; 436: 332-47.
McMurray F, Patten DA, Harper ME. Reactive oxygen species and oxidative stress in obesity—recent findings and empirical approaches. Obesity 2016; 24: 2301-10.
Ou B, Huang D, Hampsch-Woodill M, Flanagan JA, Deemer EK. Analysis of antioxidant activities of common vegetables employing oxygen radical absorbance capacity (ORAC) and ferric reducing antioxidant power (FRAP) assays: a comparative study. J Agric Food Chem 2002; 50: 3122-8.
Zujko ME, Witkowska AM, Waśkiewicz A, Mirończuk-Chodakowska I. Dietary antioxidant and flavonoid intakes are reduced in the elderly. Oxid Med Cell Longev 2015;2015.
Kalantar‐Zadeh K, Tortorici AR, Chen JL, et al. Dietary restrictions in dialysis patients: is there anything left to eat? Semin Dial 2015; 28: 159-68.
Crews DC, Kuczmarski MF, Miller III ER, Zonderman AB, Evans MK, Powe NR. Dietary habits, poverty, and chronic kidney disease in an urban population. J Ren Nutr 2015; 25: 103-10.
Limkunakul C, Sundell MB, Pouliot B, Graves AJ, Shintani A, Ikizler TA. Glycemic load is associated with oxidative stress among prevalent maintenance hemodialysis patients. Nephrol Dial Transplant 2014; 29: 1047-53.
Dounousi E, Tellis C, Pavlakou P, et al. Association between PCSK9 levels and markers of inflammation, oxidative stress, and endothelial dysfunction in a population of nondialysis chronic kidney disease patients. Oxid Med Cell Longev 2021; 2021.
Guo C-H, Wang C-L, Chen P-C, Yang T-C. Linkage of some trace elements, peripheral blood lymphocytes, inflammation, and oxidative stress in patients undergoing either hemodialysis or peritoneal dialysis. Perit Dial Int 2011; 31: 583-91.
Otocka-Kmiecik A, Orłowska-Majdak M. The role of genetic (PON1 polymorphism) and environmental factors, especially physical activity, in antioxidant function of paraoxonase. Postepy Hig Med Dosw 2009; 63: 668-77.
Kalantar-Zadeh K, Abbott KC, Salahudeen AK, Kilpatrick RD, Horwich TB. Survival advantages of obesity in dialysis patients. Am J Clin Nutr 2005; 81: 543-54.
Griffin KA, Kramer H, Bidani AK. Adverse renal consequences of obesity. Am J Physiol Renal Physiol 2008; 294: F685-96
Kalantar-Zadeh K, Rhee CM, Chou J, et al. The obesity paradox in kidney disease: how to reconcile it with obesity management. Kidney Int Rep 2017; 2: 271-81.
Segall L, Moscalu M, Hogaş S, et al. Protein-energy wasting, as well as overweight and obesity, is a long-term risk factor for mortality in chronic hemodialysis patients. Int Urol Nephrol 2014; 46: 615-21.
Aslan M, Horoz M, Çelik H. Evaluation of oxidative status in iron deficiency anemia through total antioxidant capacity measured using an automated method Turk J Haematol 2011; 28: 42-6.
Wang Y, Yang M, Lee S-G, et al. Dietary total antioxidant capacity is associated with diet and plasma antioxidant status in healthy young adults. J Acad Nutr Diet 2012; 112: 1626-35.
Vincent HK, Bourguignon CM, Taylor AG. Relationship of the dietary phytochemical index to weight gain, oxidative stress and inflammation in overweight young adults. J Hum Nutr Diet 2010;23: 20-9.