An unexpected complication in a hemodialysis patient: midodrine related A-V fistula dysfunction

Arteriovenous fistula (AVF) dysfunction is one of the common obstacles in performing hemodialysis treatment. Acute and chronic thrombosis of the fistula, stenosis, and hematomas are the major causes of the dysfunction. Here, we present an unexpected complication of midodrine use which caused in AVF dysfunction in a female patient who was suffering from hemodialysis-related hypotension.

___

  • Böchl-Daum B, Korn A, Wolzt M, Schmidt E, Eichler HG. In vivo studies on alpha-adrenergic receptor subtypes in human veins. Naunyn Schmiedebergs Arch Pharmacol 1991; 344: 302-7.
  • Prakash S, Garg AX, Heidenheim P, House AA. Midodrine appearrs to be safe and effective for dialysis-induced hypotension: a systematic review. Nephrol Dial Transplant 2003; 19: 2553-8.
  • Yen CC, Tsai CF, Luo YY, Yang HY, Liu MY, Hung PH, Hsu YH. Factors affecting fistula failure in patients on chronic hemodialysis: a population-based case-control study. BMC Nephrol. 2018 Aug 22;19: 213.