Tiroit hastalıklarında patolojik değerlendirme

Tiroit bezinde sık görülen problemler hipotiroidi, hipertiroidi, tiroidit, guatr ve tiroit nodülleridir. Hipo ve hipertiroidizmi olan hastaların çoğu biyokimyasal testlerle tanı alır. Patolojik inceleme nodüllerin değerlendirilmesinde kullanılır. Bu yazıda soliter nodüller hakkında kısa bir bilgi verilmiştir. Daha sonra ise ince iğne aspirasyon sitolojisi, biyopsi, sitolojik değerlendirme ve tiroit lezyonlarının patolojisinden bahsedilmiştir. Sonuç olarak tiroit hastalıklarında çok farklı patolojiler izlenebilir. Doğru yaklaşım için klinisyen, patolog, radyolog ve nükleer tıp uzmanını içeren multidisipliner yaklaşım gereklidir.

Pathological examination in thyroidal diseases

Common problems of thyroid gland are hypothyroidism, hyperthyroidism, thyroiditis, goitre, and thyroid nodules. Patients having hypothyroidism or hyperthyroidism are mostly diagnosed by biochemical tests. Pathological examination is used in the evaluation of nodules. This paper gives a short information about solitary nodules. Thereafter, it mentions about fine needle aspiration cytology, biopsy, cytological evaluation and pathology of thyroidal lesions. In conclusion, many types of pathological lesions can be seen in thyroid diseases. Multidisciplinary approach including clinician, pathologist, radiologist and nuclear medicine specialist is required for appropriate approach.

___

  • Baloch, Z.W., LiVolsi, V.A., 2004. Fine-needle aspiration of thyroid nodules: Past, present, and future. Endocr. Pract. 10, 234-241.
  • Boerner, S.L., Asa, L., 2010. Biopsy İnterpretation of the Thyroid. Lippincott Williams & Wilkins. Philadelphia.
  • Burlingame, O.O., Kessé, K.O., Silverman, S.G., Cibas, E.S., 2011. On-site adequacy evaluations performed by cytotechnologists: Correlation With Final Interpretations of 5241 Image-Guided Fine Needle Aspiration Biopsies. Cancer Cytopathol. 120, 177-184.
  • DeLellis, R.A., Williams, E.D., 2004. Tumours of thyroid and parathyroid. In from World Health Organization Classification of Tumors. Pathol- ogy & Genetics. Tumours of Endocrine Organs. R.A. DeLellis, R.V. Lloyd, P.U. Heitz, C. Eng C, eds. IARC Press, Lyon, 49-133.
  • Maitra, A., 2010. The Endocrine System. In from pathologic basis of disease. V. Kumar, A.K. Abbas, N. Fausto, J.C. Aster, eds. Elsevier, China, 1097-1164.
  • Rosai, J., Tallini, G., 2011. Thyroid gland. In from Rosai and Ackerman’s Surgical Pathology. J. Rosai, ed. Elsevier, China, 487-564.
  • Syed, Z.A., Cibas, E.S., 2010. The Bethesda System for Reporting Thyroid Cytopatholohy. Definitions, criteria and explanatory notes. Springer. New York.