The Effects of Phenytoin on Penicillin Produced Acute Focal Spike Focus in Rab¬bits t/ This study aimed to demonstrate quantitative phenytoin effects on focal spike focus indu¬ced by introcortical (i.c) penicilin injections. Spike frequencies prior and after phenytoin injections showed a progressive reduction. This reduction was statistically significant after the third dose of phenytoin injection (p0.05). First phenytoin injection did not affect the interval between two spikes significantly, but the interval was found delayed significantly after second (p0.05). İlk fenitoin enjeksiyonu ilâ spike arası mesafeyi belirgin olarak etkilemedi ancak, 2. enjek-siyondan (p