Fatih SUMER, Ekrem ALGÜN, Osman Zikrullah ŞAHİN, Hacer SEZGİN, Emine GÜR USLU, Kadir İLKKILIÇ, Teslime AYAZ, Serap Baydur ŞAHİN

Polikistik over sendromlu hastalarda obezitenin klinik, metabolik ve hormonal özellikler üzerine etkisi

Amaç: Bu çalışmanın amacı fazla kilolu ve obez polikistik over sendromu (PKOS)'lu hastalar ile normal kilolu PKOS'lu kadınları klinik, hormonal ve metabolik özellikler açısından karşılaştırmaktı. Yöntemler: Çalışmaya yaşları 15-39 arasında değişen 119 PKOS'lu hasta dahil edildi. Tüm hastalarda antropometrik, metabolik ve hormonal ölçümler yapıldı. Bulgular: Fazla kilolu ve obez PKOS'lu hastalarla (n=78) normal kilolu hastalar (n=41) arasında Ferriman- Gallwey hirsutizm skoru açısından bir fark saptanmadı (p=0,373). Obez grubun %71,8'inde menstruel düzensizlik görülürken, normal kilolu grupta bu oran %60,9 idi (p=0,160). HOMA-IR değerleri obez grupta anlamlı derecede daha yüksekti (1,7±0,7'ye karşın 3,3±1,7, p

The impact of obesity on clinical, metabolic and hormonal features in patients with polycystic ovary syndrome

Objectives: Our aim was to compare the clinical, hormonal and metabolic features between overweight and obese patients with PCOS and normal weight women with polycystic ovary syndrome (PCOS). Methods: 119 patients with PCOS (15-39 years) were included in the study. We evaluated anthropometric, hormonal and metabolic parameters in all patients.Results: Ferriman- Gallwey hirsutism score was similar in overweight or obese patients with PCOS (n=78) and normal weight patients with PCOS (n=41) (p=0.373). While 71.8% of the obese group had irregular menses, this ratio was 60.9% in normal weight group (p=0.160). HOMA-IR values were higher in the obese group (1.7±0.7 vs 3.3±1.7, p

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