Çiğdem ATAMAN, Şule ÖZEL, Yaprak ENGİN ÜSTÜN, Cem Yaşar SANHAL

Gebelikte HIV Enfeksiyonu

Geçtiğimiz 20 yıllık dönemde, Human Immunodeficiency Virus / İnsan Bağışıklık Yetmezlik Virüsü HIV ile enfekte olan gebelerin yönetimlerinde, ilaç teknolojisindeki gelişim ve perinatal bulaş önleme stratejilerinin daha iyi anlaşılmasına uygun olarak belirgin değişiklikler olmuştur. Gebelikte rutin HIV testi ve viral yük incelemeleri, etkili antiretroviral ilaç kullanımı, sezaryen ile doğum uygun endikasyon bulunma durumunda ve emzirmeden kaçınma en önemli güncel basamaklardır. Bu derlemede, HIV ile enfekte bir gebenin yönetimi ile ilgili en yeni yaklaşımları bildirmekteyiz.

Anahtar Kelimeler:

Gebelik, HIV, yönetim

HIV Infection In Pregnancy

Over the last 2 decades, management of the pregnant woman with human immundeficiency virus HIV has changed significantly, in line with the evolution of drug technology and a better understanding of the perinatal transmission prevention strategies. Routine HIV testing and viral load evaluation during pregnancy, effective antiretroviral drug use, cesarean section when indications are present and avoiding of breastfeeding are the actual major steps in the pregnancy follow-up. In this review, we report the latest management strategies in a pregnant woman with HIV.

Keywords:

Pregnancy, HIV, management,

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World Health Organisation. HIV/AIDS. Available at http://www.who.int/hiv/ data/en/.
Branson BM, Handsfield HH, Lampe MA, Janssen RS, Taylor AW, Lyss SB, Clark JE; Centers for Disease Control and Prevention (CDC). Revised recommendations for HIV testing of adults, adolescents, and pregnant women in health-care settings. MMWR Recomm Rep. 2006;55(RR- 14):1-17.
TC Sağlık Bakanlığı, Türkiye Halk Sağlığı Kurumu, HIV/AIDS Tanı ve Tedavi Rehberi, 2013).
Centers for Disease Control and Prevention. About HIV/AIDS. Available at: https://www.cdc.gov/hiv/basics/whatishiv.html
Centers for Disease Control and Prevention and Association of Public Health Laboratories. Laboratory Testing for the Diagnosis of HIV infecti- on: Updated Recommendations, Available at http://dx.doi.orgl10’15620l cdc.23447.
Panel on Treatment of Pregnant Women with HIV Infection and Preventi- on of Perinatal Transmission. Recommendations for Use of Antiretroviral Drugs in Transmission in the United States. Available at http://aidsinfo. nih.gov/contentfiles/lvguidelines/ PerinatalGL.pdf.
Cooper ER, Charurat M, Mofenson L, Hanson IC, Pitt J, Diaz C, Hayani K, Handelsman E, Smeriglio V, Hoff R, Blattner W, Women and Infants’ Transmission Study Group. Combination antiretroviral strategies for the treatment of pregnant HIV-1-infected women and prevention of perinatal HIV-1 transmission. J Acquir Immune Defic Syndr. 2002;29(5):484.
Obstetrics: normal and problem pregnancies. 7th edition. Philadelphia, PA: Elsevier, [2017] ©2017
Hughes B, Cu-Uvin S. Antiretroviral and intrapartum management of pregnant HIV-infected women and their infants in resource-rich settings. In: UpToDate, Post, TW (Ed), UpToDate, Waltham, MA, 2018.
Wesolowski LG, Delaney KP, Lampe MA, Nesheim SR. False-positive hu- man immunodeficiency virus enzyme immunoassay results in pregnant women. PLoS One. 2011;6(1):e16538.