Hakan EKMEKÇİ, Ayhan BÖLÜK, Haluk ŞAVLI, Münife MÜFTÜOĞLU, Murat ALADAĞ, Cemal ÖZCAN, Atilla İLHAN

The investigation of sympathetic skin response in diabetic neuropathy

Klinik ve elektrofızyolojik olarak duysal-motor periferik nöropati saptanan 41 diabetik hastada, mediyan sinirin bilekten elektriksel uyarımı ile el ve ayaktan sempatik deri cevabı (SDC) kaydedildi. Kontrol olgularının hepsinde, el ve ayaktan tüm uyarılarda SDC'ler mevcuttu. Diabetik hastaların % 14.6'inde ayakta, %4.9'unda elde SDC'ler kaydedilemedi. Diabetik hastalarda SDC bozukluğu ile hastanın yaşı, diabetin tipi, süresi, periferik nöropatinin klinik ve elektrofızyolojik bulguları arasında anlamlı bir ilişki olmadığı görüldü. Ayaklarda SDC yokluğu mesane disfonksiyonu (p< 0.05), ishal (p< 0.03) ve erkeklerde impotans (p< 0.05) gibi otonomik disfonksiyon semptomlu hastalarda daha sık bulundu. Sonuçlar SDC'nin diabetik periferal nöropatili hastalarda otonomik tutulumu göstermekte değerli bir inceleme yöntemi olduğunu telkin etmektedir. [Turgut Özal Tıp Merkezi Dergisi 1996;3(4):324-327]

Diabetik nöropatide sempatik deri cevabının araştırılması

in 41 diabetic patients with clinical and electrophysiological' evidences of motor sensory peripheral neuropathy and in 20 normal control subjects, sympathetic skin responses (SSRs) were recorded from both hands and feet by electrical stimuli to the median nerve at the wrist. The SSRs were present in all limbs of normal subjects, but were not be able to record at the feet in 14.6 % and the hands in 4.9 % of the diabetic patients. There were no significant associations between abnormalities ofSSjts, age, duration and form of diabetes, signs of peripheral neuropathy and electrophysiological abnormalities. Absence ofSSR in the feet was more frequent found in patients with symptoms of autonomic dysfunction as bladder dysfunction (p< 0.05), diarrhea (p

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