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• Samarghandian S, Azimi-Nezhad M, Mehrad-Majd H, Mirhafez SR. Thymoquinone ameliorates acute renal failure in gentamicin-treated adult male rats. Pharmacology 2015;96:(3-4):112-7.
• Mahmoud AM, Ahmed OM, Galaly SR. Thymoquinone and curcumin attenuate gentamicin-induced renal oxidative stress, inflammation and apoptosis in rats. EXCLI J 2014;13:98-110.
• Xie J, Shaikh ZA. Cadmium-induced apoptosis in rat kidney epithelial cells involves decrease in nuclear factor-kappa B activity. Toxicol Sci 2006;91(1):299-308.
• Palsamy P, Subramanian S. Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2-Keap1 signaling. Biochim Biophys Acta 2011;1812(7):719-31.
• Osman AM, Telity SA, Damanhouri ZA, Al-Harthy SE, AlKreathy HM, Ramadan WS, et al. Chemosensitizing and nephroprotective effect of resveratrol in cisplatin-treated animals. Cancer Cell Int 2015;15:6.
• Hsu CW, Lee Y, Lee CY, Lin PY. Neurotoxicity and nephrotoxicity caused by combined use of lithium and risperidone: a case report and literature review. BMC Pharmacology Toxicol 2016;17(1):59.
• Johansen KL, Smith MW, Unruh ML, Siroka AM, O’Connor TZ, Palevsky PM, Et al. Predictors of health utility among 60- day surv ivors of acute kidney injury in the veterans’ affairs/ national institutes of health acute renal failure trial network study. Clin J Am Soc Nephrol 2010;5(8):1366-72.
• Ragheb A, Attia A, Eldin WS, Elbarbry F, Gazarin S, Shoker A. The protective effect of thymoquinone, an anti-oxidant and anti-inflammatory agent, against renal injury: a review. Saudi J Kidney Dis Transpl 2009;20(5):741-52.
• Badary OA,Taha RA, Gamal el-Din AM, Abdel-Wahab MH. Thymoquinone is a potent superoxide anion scavenger. Drug Chem Toxicol 2003;26:87-98.
• Mansour MA, Nagi MN, El-Khatib AS, Al-Bekairi AM. Effects of thymoquinone on antioxidant enzyme activities, lipid peroxidation and DT-diaphorase in different tissues of mice: a possible mechanism of action. Cell Biochem Funct 2002;20(2):143-51.
• Al-Chalabi BM, Thanoon IA, Ahmed FA. Potential effect of olanzapine on total antioxidant status and lipid peroxidation in schizophrenic patients. Neuropsychobiology 2009;59(1):8-11.
• Heiser P, So mmer O, Schmidt AJ, Clement HW, Hoinkes A, Hopt UT, et al. Effects of antipsychotics and vitamin C on the formation of reactive oxygen species. J Psychopharmacol 2010;24(10)1499-504.
• Boroushaki MT, Mollazadeh H, Rajabian A, Dolati K, Hoseini A, Paseban M, et al. Protective effect of pomegranate seed oil against mercuric chloride-induced nephrotoxicity in rat. Ren Fail 2014;36(10):1581-6.
• Nagi MN, Mansour MA. Protective effect of thymoquinone against doxorubicin-induced cardiotoxicity in rats: a possible mechanism of protection. Pharmacol Res 2000;41(3):283-9.
• Nagi MN, Almakki HA, Sayed-Ahmed MM, Al-Bekairi AM. Thymoquinone supplementation reverses acetaminopheninduced oxidative stress, nitric oxide production and energy decline in mice liver. Food Chem Toxicol 2010;48(8 9):2361-5.
• Sayed-Ahmed MM, Nagi MN. Thymoquinone supplementation prevents the development of gentamicininduced acute renal toxicity in rats. Clin Exp Pharmacol Physiol 2007;34(5-6):399-405.
• Shah R, Subhan F, Ali G, Ullah I, Ullah S, Shahid M, et al. Olanzapine induced biochemical and histopathological changes after its chronic administration in rats. Saudi Pharm J 2016;24(6):698-704.
• Baratta MT, Dorman HJD, Deans SG, Biondi DM, Ruberto G. Chemical composition, antimicrobial and antioxidative activity of laurel, sage, rosemary, oregano and coriander essential oils. J Essent Oil Res 1998;10:618-27.
• Walton K, Walker R, van de Sandt JJ, Castell JV, Knapp AG, Kozianowski G, et al. The application of in vitro data in the derivation of the acceptable daily intake of food additives. Food Chem Toxicol 1999;37(129:1175-97.
• Conus P, Berk M, Cotton SM, Kader L, Macneil C, Hasty MK, et al. Olanzapine or chlorpromazine plus lithium in first episode psychotic mania: an 8-week randomised controlled trial. Eur Psychiatry 2015;30(8):975-82.
• Eder U, Mangweth B, Ebenbichler C, Weiss E, Hofer A, Hummer M, et al. Association of olanzapine-induced weight gain with an increase in body fat. Am J Psychiatry 2001;158(10):1719-22.
• Can N, Catak O, Turgut B, Demir T, Ilhan N, Kuloglu T, et al. Neuroprotective and antioxidant effects of ghrelin in an experimental glaucoma model. Drug Des Devel Ther 2015;2(9):2819-29.
• Tas U, Ayan M, Sogut E, Kuloglu T, Uysal M, Tanriverdi HI, et al. Protective effects of thymoquinone and melatonin on intestinal ischemia–reperfusion injury. Saudi J Gastroenterol 2015;21(5):284-9.
• Harma M, Harma M, Erel O. Oxidative stress in women with preeclampsia. Am J Obstet Gynecol 2005;192:656-57.
• Erel O. A new automated colorimetric method for measuring total oxidant status. Clin Biochem 2005;38(12):1103-11.
• Erel O. A novel automated method to measure total antioxidant response against potent free radical reactions. Clin Biochem 2004;37(2):112-9.
• Junge W, Wilke B, Halabi A, Klein G. Determination of reference intervals for serum creatinine, creatinine excretion and creatinine clearance with an enzymatic and a modified Jaffé method. Clin Chim Acta 2004;344(1-2):137-48.
• Prabhakar P, Reeta KH, Maulik SK, Dinda AK, Gupta YK. Protective effect of thymoquinone against high-fructose diet induced metabolic syndrome in rats. Eur J Nutr 2015;54(7):1117-27.
• Albaugh VL, Henry CR, Bello NT, Hajnal A, Lynch SL, Halle B, et al. Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents. Obesity (Silver Spring) 2006;14(1):36-51.
• Darakhshan S, Bidmeshki Pour A, Hosseinzadeh Colagar A, Sisakhtnezhad S. Thymoquinone and its therapeutic potentials. Pharmacol Res 2015;95:138-58.
• Amin B, Hosseinzadeh H. Black cumin (Nigella sativa) and its active constituent, thymoquinone: an overview on the analgesic and anti-inflammatory effects. Planta Med 2016;82(1-2):8-16.
• El-Ameen NMH, Taha MME, Abdelwahab SI, Khalid A, Elfatih F, Kamel MA, et al. Anti-diabetic properties of thymoquinone is unassociated with glycogen phosphorylase inhibition. Pharmacogn J 2015;7:406-10.
• Taka E, Mazzio EA, Goodman CB, Redmon N, Flores Rozas H, Reams R, et al. Anti-inflammatory effects of thymoquinone in activated BV-2 microglial cells. J Neuroimmunol 2015;15(286):5-12.
• El-Far AH. Thymoquinone anticancer discovery: possible mechanisms. Curr Drug Discov Technol 2015;12(12):80-9.
• Khattab MM, Nagi MN. Thymoquinone supplementation attenuates hypertension and renal damage in nitric oxide deficient hypertensive rats. Phytother Res 2007;21(5):410-14.
• Al-Saleh IA, Billedo G, El-Doush II. Levels of selenium, dl-atocopherol, dl-g-tocopherol, all-trans-retinol, thymoquinone and thymol in different brands of Nigella sativa seeds. J Food Compos Anal 2006;19:167-75.
• Bent S. Herbal medicine in the United States: review of efficacy, safety, and regulation: grand rounds at University of California, San Francisco Medical Center. J Gen Intern Med 2008;23(6):854-9.
• Schwenger E, Dumontet J, Ensom MH. Does olanzapine warrant clinical pharmacokinetic monitoring in schizophrenia? Clin Pharmacokinet 2011;50(7):415 28.
• Meyer JM, Davis VG, McEvoy JP, Goff DC, Nasrallah HA, Davis SM, et al. Impact of antipsychotic treatment on nonfasting triglycerides in the CATIE Schizophrenia Trial phase 1. Schizophr Res 2008;103(1-3):104-9.
• Newcomer JW. Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review. CNS Drugs 2005;19 Suppl 1:1-93.