İsmail Hakkı , Oğuzhan , Banu Kale , İbrahim Metin , Atila ş, Mehmet Numan öroğlu Çiriş

Tüberkulozun toplumdaki prevalansı yüksek olsa bile tiroid tubekulozu nadir görülen bir durumdur. Bu durum farklı bir klinik seyir gösterir ve asemptomatik olabilir. Postmortem çalışmalarda tiroid tüberkülozu insidansı %0.003-0.1 olarak rapor edilmesine rağmen gerçek tiroid tüberkülozu insidansı bilinmemektedir. Bu nedenle hastalığın tanısı gözden kaçabilir veya geçikebilir. Sonuç olarak hastalık ilerleyebilir ve mortalite ve morbiditenin artmasına neden olabilir. Primer tiroid tüberkülozu ilk kez 1893 yılında pulmoner tutulumun olmadığı ve servikal lenfadenopatinin eşlik ettiği guatrda hızlı büyümeyle rapor edilmiştir. Hastalığın tanısında iiab ve aspire edilen materyalin aside direçli olarak boyanması ve kültürü oldukça değerlidir. Biz burada tiroidektomi operasyonu sonrasında histopatolojik incelemede tanı konmuş graves ve hipoaktif nodülle beraber tiroid tuberkuloz olgusunu tartışacağız

Coexistence of Thyroid Tuberculosis and Graves Disease

Thyroid tuberculosis is a rare condition, even in the populations with high prevalence of tuberculosis. It shows different clinical course, and may be asymptomatic. The incidence of thyroid tuberculosis was reported as 0.003%-0.1% in a postmortem study, however, its real incidence is not known exactly. Therefore, diagnosis of the disease may be overlooked or delayed. Consequently, it may present as an advanced stage disease with increased morbidity and mortality. Primary thyroid tuberculosis that presented with rapidly enlarging goiter together with cervical lymphadenopathy without pulmonary involvement was first reported in 1893. Fine needle aspiration biopsy together with acido-resistant staining of the aspiration material and the culture are quite valuable in the diagnosis of the disease. In this paper, we will discuss a case of thyroid tuberculosis with graves and hypoactive nodule, which diagnosed by histopathological examination of postoperative thyroidectomy material

PDF

___

Khan EM, Haque I, Pandey R, Mishra SK, Sharma AK. Tuberculosis of the thyroid gland: a clinicopathological profile of four cases and review of the literature. Aust N Z J Surg 1993;63:807-10.
Simkus A, Thyroid tuberculosis. Medicina (Kaunas) 2004;40:201-4.
Mondal A, Patra DK. Efficacy of fine needle as piration cytology in the diagnosis of tuberculosis of the thyroid gland: a study of 18 cases. J Laryngol Otol 1995;109:36-8.
Tan KK. Tuberculosis of the thyoid gland--a review. Ann Acad Med Singapore 1993;22:580-2.
Bulbuloglu E, Ciralik H, Okur E, Ozdemir G, Ezberci F, Cetinkaya A. Tuberculosis of the thyroid gland: review of the literature. World J Surg 2006;30:149-55.
Pazaitou K, Chrisoulidou A, Ginikopoulou E, Angel J, Destouni C, Vainas I. Primary tuberculosis of the thyroid gland: report of three cases. Thyroid 2002;12):1137-40.
El Malki HO, El Absi M, Mohsine R, et al. Tuberculosis of the thyroid. Diagnosis and treatment. Ann Chir 2002;127:385-7.
Onyango RO. State of the globe: Tracking tuberculosis is the test of time. J Glob Infect Dis 2011;3:1-3.
Akbulut S, Sogutcu N, Arikanoglu Z, Bakir S, Ulku A, Yagmur Y. Thyroid tuberculosis in southeastern Turkey: Is this the resurgence of a stubborn disease? World J Surg 2011;35:1847-52.
Bulbuloglu E,Ciralik H, Okur E, Ozdemir G, Ezberci G, Cetinkaya A. Tuberculosis of the thyroid gland: review of the literature. World J Surg 2006;30:149-155.
Kapoor VK, Subramani K, Das SK, Mukhopadhyay AK, Chattopadhyay TK. Tuberculosis of the thyroid gland associated with thyrotoxicosis. Postgrad Med J 1985;61:339-40.
Tabacu E, Galie N, Galbenu P, Mitrea M. Thyroid tuberculosis a clinical case. Pneumologia 2000;49:41-4.
Fung LM, Ma RC, Chow CC, Cockram CS, Infective thyroiditis in two cases of systemic lupus erythematosus. Hong Kong Med J 2004;10:344-6.
Milcu SM, Spandonide T, Saim A, Tuberculous thyroiditis cured by drug therapy. Endocrinologie 1981;19:261-3.
Lioté HA, Spaulding C, Bazelly B, Milleron BJ, Akoun GM. Thyroid tuberculosis associated with mediastinal lymphadenitis. Tubercle 1987;68:229-31.