Primary adenocarcinoma of urinary bladder Initially diagnosed as metastatic adenocarcinoma: A case report
Mesanenin primer adenokarsinomları mesaneyi metastaz veya direkt yayılım yolu ile sekonder olarak tutan adenokarsinomlar ile morfolojik olarak benzerlik gösteren ve bazen tanısal güçlü e yol açan nadir neoplazmlardır. Tümörün primer orijinini belirlemek, tümörü evreleyebilmek, uygun tedaviye ba lamak ve prognozu tahmin edebilmek açısından önemlidir. Bu makalede ba ka bir merkezde metastatik adenokarsinom tanısı almı olan mesanenin primer adenokarsinom olgusunu sunduk ve mesanenin primer adenokarsinomunun tanısal ve histopatolojik özelliklerini literatürler e li inde gözden geçirdik.
Metastatik adenokarsinom tanısı almış primer mesane adenokarsinomu: Olgu sunumu
Primary adenocarcinoma of the urinary bladder is a rare neoplasm sometimes causing diagnostic challenge because it can be indistinguishable morphologically from adenocarcinoma secondarily involving the bladder by metastasis or direct extension. Identifying the primary origin of the tumor is important in staging, determining appropriate therapy and assessing prognosis. We report herein a case of primary adenocarcinoma of the bladder misdiagnosed as metastatic adenocarcinoma and reviewed the histopathologic features and diagnostic characteristics of primary adenocarcinoma of bladder in view of literature.
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- 1. Edwards PD, Hurm RA, Jaeschke WH. Conversion of cystitis glandularis to adenocarcinoma. J Urol 1972;108(4):568-70.
- 2. Gill HS, Dhillon HK, Woodhouse CR. Adenocarcinoma of the urinary bladder. Br J Urol 1989;64(2):138-42.
- 3. Mazzucchelli R, Scarpelli M, Montironi R. Mucinous adenocarcinoma with superficial stromal invasion and villous adenoma of urachal remnants: a case report. J Clin Pathol 2003;56(6):465-7.
- 4. Grignon DJ, Ro JY, Ayala AG, Johnson DE, Ordonez NG. Primary adenocarcinoma of the urinary bladder. A clinicopathologic analysis of 72 cases. Cancer 1991;67(8):2165-72.
- 5. Anderstrom C, Johansson SL, von Schultz L. Primary adenocarcinoma of the urinary bladder. A clinicopathologic and prognostic study. Cancer 1983;52(7):1273-80.
- 6. Pathology of the Urinary Bladder in Young RH editor. Non- neoplastic epithelial abnormalities and tumorlike lesions. New-York, Churchill Livingstone; 1989, pg 1-65.
- 7. Susmano D, Rubenstein AB, Dakin AR, Lloyd FA. Cystitis glandularis and adenocarcinoma of the bladder. J Urol 1971;105(5):671-4.
- 8. Young RH, Bostwick DG. Florid cystitis glandularis of intestinal type with mucin extravasation: a mimic of adenocarcinoma. Am J Surg Pathol 1996;20(12):1462-8.
- 9. WHO classification of tumors, in Eble JN, Sauter G, Epstein IJ editors. Pathology and Genetics of Urinary System and Male Genital Organs, ; 2004, pg90-157.
- 10. Abenoza P, Manivel C, Fraley EE. Primary adenocarcinoma of urinary bladder. Clinicopathologic study of 16 cases. Urology 1987;29(1):9-14.
- 11. Tran KP, Epstein JI. Mucinous adenocarcinoma of urinary bladder type arising from the prostatic urethra. Distinction from mucinous adenocarcinoma of the prostate. Am J Surg Pathol 1996;20(11):1346-50.
- 12. Torenbeek R, Lagendijk JH, Van Diest PJ, Bril H, van de Molengraft FJ, Meijer CJ. Value of a panel of antibodies to identify the primary origin of adenocarcinomas presenting as bladder carcinoma. Histopathology 1998;32(1):20-7.
- 13. Wang HL, Lu DW, Yerian LM, Alsikafi N, Steinberg G, Hart J, et al. Immunohistochemical distinction between primary adenocarcinoma of the bladder and secondary colorectal adenocarcinoma. Am J Surg Pathol 2001;25(11):1380-7.
- 14. el-Mekresh MM, el-Baz MA, Abol-Enein H, Ghoneim MA. Primary adenocarcinoma of the urinary bladder: a report of 185 cases. Br J Urol 1998;82(2):206-12.
- 15. Corica FA, Husmann DA, Churchill BM, Young RH, Pacelli A, Lopez-Beltran A, et al. Intestinal metaplasia is not a strong risk factor for bladder cancer: study of 53 cases with long-term follow-up. Urology 1997;50(3):427-31.