DENTAL UYGULAMALAR İÇİN YENİ NESİL FONKSİYONEL NANOKOMPOZİTLERİN HAZIRLANMASI VE KARAKTERİZASYONU

Bu çalışmada, yeni nesil antimikrobiyal, azol içerikli dental kompozit geliştirilmiş ve değerlendirilmiştir. 1,2,4-Triazol, 3-amino-1,2,4-t-Triazol ve 5-Aminotetrazol fonksiyonel SiO2 nanopartiküller, reçine içerisine homojen olarak dağıtılarak polimerizasyon gerçekleştirilmiştir. Azol içerikli dental kompozitler, azol içerikli nanopartiküllerin BisGMA/TEGDMA reçineye bağlanmasını doğrulamak için FTIR spektroskopisi ile karakterize edildi. Taramalı elektron mikroskop analiz sonuçları, azollü nanopartiküllerin dental kompozit içerisinde homojen dağılımını doğrulamıştır. X-ışını kırınım çalışmaları, malzemelerin amorf karakterinin azollü nanopartiküllerin yapıya katılması ile geliştiğini göstermiştir. Termogravimetrik ve diferansiyel taramalı kalorimetrik analizleri ile düşük sıcaklıklarda, azollü dental kompozitlerin termal kararlılığının nanopartikül içeriğinin artışı ile büyük oranda arttığı belirlenmiştir. Dental kompozitlerin suda çözünürlükleri ve emilimleri 37ºC’ de saf su içerisinde bekletilerek gözlemlenmiş, ISO şartlarına uygunluğu görülmüştür. Azol içeren dental kompozitlerin antimikrobiyal aktivite göstermesi, diş hekimliği uygulamalarında kullanılabileceğinin kanıtıdır.

Anahtar Kelimeler:

dental kompozitler, nanopartiküller, triazol, 3 amino triazole, 5 amino tetrazole

Production and Characterization of Novel Functional Nanocomposites For Dental Applications

In this study, a new generation antimicrobial azole-containing dental composite has been developed and evaluated. Polymerization has been realized by dispersing 1,2,4-Triazole, 3-amino-1,2,4-t-Triazole ve 5-Aminotetrazole functional SiO2 nanoparticles homogeneously into the resin. Azole-containing dental composites were characterized by FTIR spectroscopy to confirm the binding of azole-containing nanoparticles to BisGMA/TEGDMA resin. Scanned electron microscopic analysis results confirmed the homogeneous distribution of azole nanoparticles in the dental composites. X-ray diffraction studies have shown that the amorphous character of the materials is improved by the incorporation of azole nanoparticles into the structure. By thermogravimetric and differential scanning calorimetric analyzes, it has been determined that the thermal stability of azole dental composites greatly increased with the increase of nanoparticle content at low temperatures. The solubility and absorption of dental composites in water have been observed by keeping them in 37ºC distilled water, and their compliance with ISO requirements has been observed. The fact that the azole-containing dental composites show antimicrobial activity is the proof that they can be used in dentistry applications.

Keywords:

dental composites, nanoparticles, triazole, 3 amino triazole, 5 amino tetrazole,

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