Long-Term follow-up of multicystic dysplastic kidneys: A single center experience

Amaç: Multikistik displastik böbrek (MKDB), böbreğin en sık görülen gelişimsel anomalilerinden birisidir. Yaklaşık olarak 4300 canlı doğumda bir görülmektedir. Çalışmamızın amacı, MKDB'li çocukların takip prosedürünün mevcut sonuçlarımızı literatür ile karşılaştırılması yoluyla gözden geçirmektir.Yöntem: Antenatal tanılı MKDB'li 36 çocuk hastanın izlem sonuçları değerlendirildi.Bulgular: Hastaların %94,4'ünde karşı taraf böbrekte kompanzatris hipertrofi görüldü. Tam involüsyon süresi ortalama 22,97±32,63 ay idi. İkisi ilaç tedavisine dirençli hipertansiyon ve 2'si ebeveyn endişesi nedeniyle olmak üzere 4 hastaya nefrektomi yapıldı. Vezikoüreteral reflü (VUR) en sık görülen anomali olarak saptandı. Beş (%13,8) hastada VUR saptandı. Saptanan VUR tüm olgularda düşük dereceliydi ve DMSA'da skar saptanmadı.Sonuç: Çalışmamızın sonuçlarına göre MKDB genellikle iyi huylu bir hastalıktır. Ultrasonografi hastaların izleminde yeğlenebilecek girişimsel olmayan ve maliyet etkin bir yöntemdir. Ultrasonografi bulguları renal parenkimal defekt ve şüpheli VUR bulguları göstermedikçe rutin VCUG yapılması gerekmeyebilir

Multikistik displastik böbreklerin uzun dönem izlemi: Tek merkez deneyimi

Objective: Multicystic dysplastic kidney (MCDK) is one of the most common developmental anomalies of the kidney with an incidence of approximately 1 in 4300 live births. The goal of our study was to review our follow-up procedure of children with MCDK through this study via comparison of outcomes with the literature. Methods: Follow-up outcomes of 36 pediatric patients with antenatally detected unilateral MCDK were assessed. Results: The compensatory renal hypertrophy of the contralateral kidney was seen in 94.4% of the patients and mean complete involution time was 22.97±32.63 months. Four patients underwent nephrectomy because of hypertension resistant to medication in 2 patients and parental concern in 2 patients. Vesicoureteral reflux (VUR) was the most frequent anomaly detected in 5 (13.8%) patients. VUR were low grade in all patients and any scar was not detected on DMSA. Conclusion: The results of our study showed that MCDK is usually a benign disease. Ultrasound is a noninvasive and cost- effective method of choice in follow-up. A VCUG may not be routinely required in MCDK patients unless renal US reveals signs of suspect VUR or renal parenchymal defects

Kaynakça

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