0.05), göz içi basıncının Grup II' de (18,74 ± 1,82 mmHg) Grup I' e (16,02±1,08 mmHg) göre istatistiksel açıdan anlamlı derecede arttığı saptandı (p<0.05). Sonuç olarak, süksinilkolin gibi hızlı ve iyi entübasyon koşulları sağlaması ve göz içi basıncında belirgin artışa yol açmaması nedeniyle rokuronyumun oftalmik cerrahide, acil ve tok hastalarda, obstetrik olgularda uzun etkili nöromusküler bloker kullanımı sorun olmadığında rahatlıkla seçilebilecek bir ajan olduğu inancındayız. This study was designed to compare the intraocular pressure effect, intubation conditions and onset time of rocuronium and succinylcholine during rapid sequence induction of anaesthesia using propofol. Thirty nonopthalmologic patients of ASA I-II risk group who scheduled for elective cesarean section included in this study. Patients allocated to one of two groups randomly. Anaesthesia was induced with propofol 2mg/kg until loss of verbal response. This was followed by rocuronium 0.6 mg/kg (groupI, n-15) or succinylcholine 1 mg/kg (group II, n=15). Orotracheal intubation was performed when reached to 100 % T1 block (onset time) which was measured by TOP Guard (Organon Technika). Intubation conditions, onset time and intraocular pressure (IOP) were recorded. IOP was measured by Shiotz tonometer and it was recorded at before induction, after induction, at T1 100 % block and immediately after intubation. The onset time was significantly less in group II than group I (41,34±6,67 s vs 66,6±22,4 s; p<0.01). Intubation conditions were equally good in both groups and there were no significant difference between groups (p>0.05). IOP in group II was significantly greater than group I (18,74±1,82 mmHg vs 16,02±1,08 mmHg; p<0.05).We conclude that, with its rapid onset time and lack of intra-ocular pressure effects, rocuronium is may be the relaxant of choice in patients with opthalmological surgery, obstetrics and emergency procedures where a long lasting relaxant is not contraindicated.">
[PDF] Rokuronyumun göz içi basıncına etkisi | [PDF] The effects of rocuronium on the intraocular pressure
0.05), göz içi basıncının Grup II' de (18,74 ± 1,82 mmHg) Grup I' e (16,02±1,08 mmHg) göre istatistiksel açıdan anlamlı derecede arttığı saptandı (p<0.05). Sonuç olarak, süksinilkolin gibi hızlı ve iyi entübasyon koşulları sağlaması ve göz içi basıncında belirgin artışa yol açmaması nedeniyle rokuronyumun oftalmik cerrahide, acil ve tok hastalarda, obstetrik olgularda uzun etkili nöromusküler bloker kullanımı sorun olmadığında rahatlıkla seçilebilecek bir ajan olduğu inancındayız.">
0.05), göz içi basıncının Grup II' de (18,74 ± 1,82 mmHg) Grup I' e (16,02±1,08 mmHg) göre istatistiksel açıdan anlamlı derecede arttığı saptandı (p<0.05). Sonuç olarak, süksinilkolin gibi hızlı ve iyi entübasyon koşulları sağlaması ve göz içi basıncında belirgin artışa yol açmaması nedeniyle rokuronyumun oftalmik cerrahide, acil ve tok hastalarda, obstetrik olgularda uzun etkili nöromusküler bloker kullanımı sorun olmadığında rahatlıkla seçilebilecek bir ajan olduğu inancındayız. This study was designed to compare the intraocular pressure effect, intubation conditions and onset time of rocuronium and succinylcholine during rapid sequence induction of anaesthesia using propofol. Thirty nonopthalmologic patients of ASA I-II risk group who scheduled for elective cesarean section included in this study. Patients allocated to one of two groups randomly. Anaesthesia was induced with propofol 2mg/kg until loss of verbal response. This was followed by rocuronium 0.6 mg/kg (groupI, n-15) or succinylcholine 1 mg/kg (group II, n=15). Orotracheal intubation was performed when reached to 100 % T1 block (onset time) which was measured by TOP Guard (Organon Technika). Intubation conditions, onset time and intraocular pressure (IOP) were recorded. IOP was measured by Shiotz tonometer and it was recorded at before induction, after induction, at T1 100 % block and immediately after intubation. The onset time was significantly less in group II than group I (41,34±6,67 s vs 66,6±22,4 s; p<0.01). Intubation conditions were equally good in both groups and there were no significant difference between groups (p>0.05). IOP in group II was significantly greater than group I (18,74±1,82 mmHg vs 16,02±1,08 mmHg; p<0.05).We conclude that, with its rapid onset time and lack of intra-ocular pressure effects, rocuronium is may be the relaxant of choice in patients with opthalmological surgery, obstetrics and emergency procedures where a long lasting relaxant is not contraindicated.">
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