Investigation of the aortic pulse wave velocity in hypertensive and normotensive obese subjects

Arteryel sertliğin halihazırda ''altın standart'' ölçümü aortik (karotis-femoral) nabız dalga hızıdır.Obezite genellikle hipertansiyon ve hiperglisemi gibi kardiyovasküler risk faktörleri ile birliktelik gösteren bir hastalıktır. Biz hipertansif ve normotansif obez olgularda, Aortik nabız dalga hızı ve vücut kitle indeksi arasındaki ilişkiyi araştırmayı amaçladık.Kan basıncı ve vücut kitle indeksine göre iki grup olmak üzere toplam 109 olgu alındı. Vücut kitle indeksine göre olgular 30.0-34.9 kg/ m2 olanlar Clas I, >=35 kg/m2 olanlar Clas II olarak tanımlandı. Sonrasında Clas I ve II grupları kan basıncına göre iki gruba normotansif-Clas I, II ve hipertansif-Clas I, II olarak ayrıldı. Tüm grupta (n:109) nabız dalga hızı, yaş, sistolik kan basıncı ve diyastolik kan basıncı ile korelasyon göstermekteydi (sırasıyla, r=0.229; p=0.017, r=0.301; p=0.001 ve r=0.323; p=0.001). Nabız dalga hızının Clas I ve Clas II grupta vücut kitle indeksi ile korelasyonu yoktu. Bu verilere göre, vücut kitle indeksi 30 kg/ m2 üzerindeki olgularda nabız dalga hızının artması vücut kitle indeksi ile ilişkili değildir, fakat yaş, sistolik ve diyastolik kan basıncı ile ilişkili olabilir.

Hipertansif ve normotansif obez olgularda aortik nabız dalga hızının incelenmesi

Aortic pulse wave velocity is currently the 'gold standard' measure of arterial stiffness.In this study we aimed to investigatethe relationships betweenAortic pulse wave velocity and body mass index in hypertensive andnormotensiveobesesubjects.A total of109 obese subjects were divided into two groups according to arterial blood pressures andbody mass index. Subjects with a body mass index of 30.0-34.9 kg/m2 were defined as Class I, and >=35.0 kg/m2 as Class II. Then Class I and II groups were divided into two groups according to blood pressures as normotensive-Class I, II and hypertensive-Class I, II.In the whole group (n:109) pulse wave velocity was significantly correlated with age, systolic blood pressure and diastolic blood pressure (r=0.229; p=0.017, r=0.301; p=0.001 and r=0.323; p=0.001, respectively). Pulse wave velocity was not significantly correlated with body mass index neither in the whole group nor in the Class I and Class II groups.These results suggest that in the patients with a body mass index of >=30.0 kg/m2, increase ofpulse wave velocity is not associated with body mass index, but can be related with age, systolic and diastolic blood pressure.

Kaynakça

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