The prevalence of fetal neural abnormalities detected by ultrasonography in southeast part of Turkey

AMAÇ: Bu çalışmanın amacı, Türkiye’de bir Üniversite hastanesinde prenatal ultrasonografi ile belirlenen fetal nöral anomalilerin prevalansını belirlemekti. GEREÇ VE YÖNTEM: Bu bir tek merkezli retrospektif çalışmadır. Prenatal ultrasonografik görüntülerin tamamı Gaziantep Üniversitesi Tıp Fakültesi Radyoloji Anabilim Dalı’na Ocak 2000 ve Mart 2006 tarihleri arasında gönderilen gebelerin ultrasonografilerinin geriye dönük olarak araştırılması ile elde edildi.Fetal ultrasonografiler yüksel rezolusyonlu cihazlarla yapıldı ve tüm fetal nöral anomaliler kaydedildi. BULGULAR: Yapılan 3782 adet fetal ultrasonografi arasında 32 tane (%0,85) fetus nöral anomaliliydi. Bu 32 hastanın, 6 tanesinin nöral anomalisi hızlı obstetric manyetik rözenans görüntülemesi kullanılarak doğrulandı.Belirlenen fetal nöral anomaliler; yedi Chiari II (%0,18), bir Chiari III (%0,02), üç Meckel- Gruber sendromu (%0,08), sekiz anensefali (%0,21), iki şizensefali (%0,05), iki kolposefali (%0,05), iki koroid pleksus kisti (%0,05), bir araknoid kist (%0,02), iki oksipital ensefalosel ve Dandy-Walker malformasyonu (%0,05) ve torakal meningomyelosel (%0,02). SONUÇ: Bu çalışmanın sonuçları gösterdi ki, Gaziantep Üni - versitesi Radyoloji Anabilim Dalı’nda fetal nöral anomalilerin genel olarak prevalansı mevcut tıp literatürü ile uyum luy du. Bununla birlikte, şizensefali prevalansının belirgin derecede yük sek olduğu daha önce rapor edilmişti ve bunun çalışmada kullanılan yüksek rezolusyonlu yüksek sensitiviteli ultrasonografi cihazlarına bağlı olduğu düşünülmüştü.

Güneydoğu Anadolu Bölgesi’nde ultrasonografi ile belirlenen fetal nöral anomalilerin prevalansı

OBJECTIVE: The aim of this study was to determine the prevalence of fetal neural abnormalities detected by prenatal ultrasonography in a university hospital in Turkey, and to review the points critical on the diagnosis of each fetal neural abnormality. STUDY DESING: This is a single center retrospective study. The prenatal ultrasonographic imaging of all the women referred to Department of Radiology of Gaziantep University Medical School, between January 2000 and March 2006, for fetal ultrasonography were reviewed. Fetal ultrasonographies were performed with high resolution sonography devices and all the fetal neural abnormalities were recorded. RESULTS: A total of 32 (0.85%) fetuses with neural abnormalities among 3782 fetal ultrasonographies were detected. Of these 32, six were also confirmed to have fetal neural abnormality by using fast obstetric magnetic resonance imaging. The identified fetal neural abnormalities were as follows: seven Chiari II (0,18%), one Chiari III (0,02%), three Meckel-Gruber syndrome (0,08%), eight anencephaly (0,21%), two schizencephaly (0,05%), two colpocephaly (0,05%), two choroid plexus cysts (0,05%), one arachnoid cyst (0,02%), two Dandy-Walker Malformation with occipital encephalocele (0,05%) and one thoracal meningomyelocele (0,02%). CONCLUSIONS: The results of this study showed that the overall prevalence of fetal neural abnormalities in the Department of Radiology in Gaziantep University is relevant to current medical literature. However, the prevalence of schizencephaly is remarkably higher than previously reported, which is thought to be due to high sensitivity of high resolution sonography devices used in this study.

Kaynakça

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Kaynak Göster

  • ISSN: 1300-4751
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 1995

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