The effect of maternal smoking on the height, weight and apgar scores of the newborn and on placental parameters

AMAÇ: Bu çalışmanın amacı sigara kullanımının yenidoğanın ağırlığı, boyu, birinci ve beşinci dakika apgar skorları; plasentanın ağrılığı, yüzey alanı, kotiledon sayısı ve umblikal kordun coiling indeksi üzerindeki etkisini belirlemekti. GEREÇ VE YÖNTEM: Bu çalışma Ocak 2003-Ocak 2004 yılları arasında Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi ve Gülhane Askeri Tıp Akademisi Anatomi Anabilim Dalı’nda yürütüldü ve 258 taze doğmuş insan plasentası üzerinde çalışıldı. Plasentalar kan ve membranları ayrıldıktan sonra makroskopik incelendi. Umblikal kord plasental diskten 1cm uzaklıktan kesildi. Maternal sigara kullanımının yenidoğan ve plasental parametreler üzerinde etkisi olup olmadığını görmek için hastalar iki gruba ayrıldı: sigara bağımlıları (46 vaka) ve sigara kullanmayanlar (212 vaka) ve bu gruplar plasental parametreler ve yenidoğanın APGAR skorları, doğum ağırlıkları ve boyları açısından karşılaştırıldı. BULGULAR: Bu çalışmada iki grup arasında plasental yüzey alanı ve 1. dakika Apgar skorları açısından istatistiksel olarak anlamlı fark olduğu görüldü (p

Maternal sigara kullanımının yenidoğanın boyu ağırlığı ve apgar skoru ile plasental parametreler üzerindeki etkisi

OBJECTIVE: The aim of this study was to evaluate the effect of smoking on weight, length, 1. and 5. minute apgar scores of newborn and weight, surface area, number of cotyledon of placenta, and coiling index of umbilical cord. STUDY DESIGN: This study was run in Etlik Zübeyde Hanım Maternity And Women&#8217;s Health Academic and Research Hospital and Gülhane Military Medical Academy Department of Anatomy between January 2003 to January 2004 and perfomed on 258 freshly delivered human placentas. The collected placentas were examined macroscopically, after removing the excess blood, and membrane and the umbilical cord was cut at 1 cm from the placental disc. In order to see if maternal smoking influences newborn and placental parameters, patients were divided into two groups: habitual smokers (46 women) and non-smokers (212 women) and these groups were compared according to placental parameters and newborn APGAR scores,weight and length of newborn. RESULTS: It is determined that placental surface area and Apgar score at 1minute were statistically different among the groups (p<0.05). Number of cotyledon, placental weight, coiling index of umblical cord, fetal length and weight and Apgar at 5 minutes were not different between smokers and non-smoker mothers. CONCLUSION: Smoking seems to effect placental surface area and neonatal Apgar score at 1 minute. Large randomized prospective studies are needed to reveal exact relationship between maternal smoking and fetal placental parameters.

Kaynakça

1. Simpson WJ. A preliminary report on cigarette smoking and the incidence of prematurity. Am J Obstet Gynecol. 1957 Apr;73(4):807-15.

2. van der Velde WJ, Treffers PE. Smoking in pregnancy: the influence on percentile birth weight, mean birth weight, placental weight, menstrual age, perinatal mortality and maternal diastolic blood pressure. Gynecol Obstet Invest. 1985;19(2):57-63.

3. Mochizuki M, Maruo T, Masuko K, Ohtsu T. Effects of smoking on fetoplacental-maternal system during preg nancy. Am J Obstet Gynecol. 1984 Jun 15;149(4):413-20.

4. Beaulac-Baillargeon L, Desrosiers C. Caffeine-cigarette interaction on fetal growth. Am J Obstet Gynecol. 1987 Nov;157(5):1236-40.

5. Newnham JP, Patterson L, James I, Reid SE. Effects of maternal cigarette smoking on ultrasonic measurements of fetal growth and on Doppler flow velocity waveforms. Early Hum Dev. 1990 Oct;24(1):23-36.

6. Pfarrer C, Macara L, Leiser R, Kingdom J. Adaptive angiogenesis in placentas of heavy smokers. Lancet. 1999 Jul 24;354(9175):303.

7. Larsen LG, Clausen HV, Jonsson L. Stereologic examination of placentas from mothers who smoke during pregnancy. Am J Obstet Gynecol. 2002 Mar;186(3):531-7.

8. Wingerd J, Christianson R, Lovitt WV. Placental ratios in white and black women: relation to smoking and anemia. Am J Obstet Gynecol 1976; 124: 671-5.

9. POTUR B: Placental abruption and intrauterine fetal death with acute excessive cigarette smoking. Turkiye Klinikleri J Gynecol Obst 2002, 12:64-65

10. Butler NR, Alberman ED. Perinatal problems. In: The second report of the 1958 British Perinatal Mortality Survey. Edinburgh: Livingstone; 1969. p.128-132.

11. de Haas JH. Parental smoking. Its effects on fetus and child health. Eur J Obstet Gynecol Reprod Biol. 1975; 5(5):283-96.

12. Butler NR, Goldstein H, Ross EM. Cigarette smoking in pregnancy: its influence on birth weight and perinatal mortality. Br Med J. 1972 Apr 15;2(806):127-30.

13. Anderson GD, Blidner IN, McClemont S, Sinclair JC. Determinants of size at birth in a Canadian population. Am J Obstet Gynecol. 1984 Oct 1;150(3):236-44.

14. Cliver SP, Goldenberg RL, Cutter GR, Hoffman HJ, Davis RO, Nelson KG. The effect of cigarette smoking on neonatal anthropometric measurements. Obstet Gynecol. 1995 Apr;85(4):625-30.

15. Williams LA, Evans SF, Newnham JP. Prospective cohort study of factors influencing the relative weights of the placenta and the newborn infant. BMJ. 1997 Jun 28; 314 (7098):1864-8.

16. Hindmarsh PC, Geary MP, Rodeck CH, Kingdom JC, Cole TJ. Intrauterine growth and its relationship to size and shape at birth. Pediatr Res. 2002 Aug;52(2):263-8.

17. Williams PL, Bannister LH, Berry MM. Human Placenta In: Gray’s Anatomy 38th ed, Edinburgh 1995 Churchill Livingstone; 1995 p. 166-167.

18. Cunningham FG, Clark SL, Gant NF. Abnormalities of the umbilical cord. In Williams Obstetrics, 21st edition, New York, McGraw-Hill Medical Publishing Division; 2001. p. 831-835.

19. de Laat MW, Franx A, van Alderen ED, Nikkels PG, Visser GH. The umbilical coiling index, a review of the literature. J Matern Fetal Neonatal Med. 2005 Feb; 17(2):93-100.

20. Machin GA, Ackerman J, Gilbert-Barness E. Abnormal umbilical cord coiling is associated with adverse perinatal outcomes. Pediatr Dev Pathol. 2000 Sep-Oct;3(5):462-71

21. Benirschke K. Obstetrically important lesions of the umbilical cord.: J Reprod Med. 1994 Apr;39 (4): 262-72.

22. Dado GM, Dobrin PB, Mrkvicka RS. Venous flow through coiled and noncoiled umbilical cords. Effects of external compression, twisting and longitudinal stretching. J Reprod Med. 1997 Sep;42(9):576-80.

23. Strong TH, Finberg HJ, Mattox JH. Antepartum diagnosis of noncoiled umbilical cords. Am J Obstet Gynecol 1994;170:1729-1733.

24. Degani S, Lewinsky RM, Berger H. Sonographic estimation of umbilical coiling index and correlation with Doppler flow characteristics. Obstet Gynecol 1995; 86: 990-993.

25. Rana J, Ebert GA, Kappy KA. Adverse perinatal outcome in patients with an abnormal umbilical coiling index. Obstet Gynecol 1995;85:573-577.

26. Ercal T, Lacin S, Altunyurt S. Umbilical coiling index: is it a marker for the foetus at risk? Br J Clin Pract 1996;50: 254-256

Kaynak Göster

  • ISSN: 1300-4751
  • Yayın Aralığı: Yılda 3 Sayı
  • Başlangıç: 1995

4.9b 2.5b

Sayıdaki Diğer Makaleler

Prenatal diagnosis of osteogenesis imperfecta

Suna ÖZDEMİR, Zuhal YAPICI, Gülçin ALTINOK, YASEMİN ALANAY, MEHMET SİNAN BEKSAÇ

Chromosome abnormalities in Turkish men with primary infertility

Tayfun GÜNGÖR, Mine PEKTAŞ KANAT, Müfit M. GÜNEL, Leyla MOLLAMAHMUTOĞLU

Neonatal loss secondary to third trimester chemotherapy for maternal breast cancer

İlknur İNEGÖL, Özgür ÖZYÜNCÜ, Işın ÜREYEN, Sadettin KILIÇKAP, Yusuf Alper KILIÇ, SEZCAN MÜMÜŞOĞLU, MEHMET SİNAN BEKSAÇ

Minimally invasive approach for combined cholecystectomy and total hysterectomy with ligasure

İlknur GÜMÜŞ İNEGÖL, Önder SÜRGİT, Serap SİMAVLI, İkbal KAYGUSUZ

The effect of maternal smoking on the height, weight and apgar scores of the newborn and on placental parameters

R. Sinan KARADENİZ, M. Metin ALTAY, Yeşim TEKİN BEYOĞLU, Necdet KOCABIYIK, Hasan OZAN, Orhan GELİŞEN

The prevalence of fetal neural abnormalities detected by ultrasonography in southeast part of Turkey

Ayhan ÖZKÜR, Selim KERVANCIOĞLU, Ebru DİKENSOY, Aylin AKÇALI, Reşat KERVANCIOĞLU, MEHMET METİN BAYRAM

Cytogenetic investigation in couples with recurrent abortion and poor obstetric history

Ebru ETEM ÖNALAN, HÜSEYİN YÜCE, Deniz EROL, Şükriye DEVECİ DERYA, Hüsnü ÇELİK, Halit ELYAS

Death of the spouse during pregnancy giving the bad news and the management

KAZIM EMRE KARAŞAHİN, İbrahim ALANBAY, Mutlu ERCAN, İskender BAŞER

Determining the risk of premenopausal endometrial carcinoma by analysing expression of c-erb-B2 in patients with polycystic ovary syndrome

Feyza ARMAN, Tayfun GÜNGÖR, A. Levent ŞİRVAN, S. Özlem ALTINKAYA, Banu MAT, Yeksin HELVACIOĞLU, Ümit BİLGE, Leyla MOLLLAMAHMUTOĞLU

Prenatal diagnosis of Tay-sachs disease

Özgür ÖZYÜNCÜ, DERMAN BAŞARAN, Asuman ÖZKARA, Meral TOPÇU, MEHMET SİNAN BEKSAÇ