Stronsiyum Katkılı Biyocam ve Bakır Nanoparçacıklarından 3D Kompozit Yapı İskelesi Üretimi

Bu çalışmada, çözücü döküm ve tanecik uzaklaştırma yöntemi kullanılarak, çok işlevli yapı iskelelerinin geliştirilmesi için ilgili iyonlarla BG / polimer 3D kompozit yapı iskelelerinin üretilmesi amaçlanmıştır. Gözenekli yapıya sahip yapı iskeleleri başarıyla sentezlenmiş ve yapı iskelelerinin mikroyapısında iyi bir gözenek bağlantısının bulunduğu gözlemlenmiştir. Kompozit yapı iskelelerinin in vitro biyoaktivitesi; Taramalı Elektron Mikroskopisi (SEM), X-ışını kırınımı ve Fourier-Dönüşümlü Kızılötesi Spektroskopi ölçümleri ile teyit edilmiştir. Bunun dışında, terapötik iyonların salınımının; SBF'de kalma sürelerinin bir fonksiyonu olarak, stronsiyum ve bakır iyonları için sırasıyla 1.27-5.36 ppm ve 1.53-5.42 ppm aralığında değiştiği belirlenmiştir. Bu sonuç yapı iskelelerinin, kemik dokusu rejenerasyonunun belirleyicisi olan SBF ortamına, stronsiyum ve bakır dozlarının kontrollü olarak verebileceğini göstermiştir.

Anahtar Kelimeler:

: Kompozit Yapı İskelesi, Biyoaktif Cam, Terapötik İyonlar

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