Zehra KURDOGLU, Mertihan KURDOGLU, Gulcin AY, Gulay BULUT

Nonfunctional Pelvic Retroperitoneal Paraganglioma Mimicking Postmenopausal Adnexal Mass

Paraganglioma, ekstraadrenal kromafin hücrelerinden oluşan paraganglial dokudan köken alan nadir bir tümördür. Tümörün pelvik ve retroperitoneal lokalizasyonu oldukça nadirdir ve adneksiyal kitleyi taklit edebilir. Bu bölgedeki paragangliomanın tanısı zordur. Kesin tanı, sadece total eksizyon ve tümörün histopatolojik incelemesi sonrasında konulabilir. Bu makalede, ilk kez, postmenopozal adneksiyal kitleyi taklit eden nonfonksiyonel retroperitoneal paragangliomalı postmenopozal kadın olguyu sunduk. Bu vakada vurgulanan; ekstraadrenal paragangliomanın karın ağrısı gibi spesifik olmayan semptom varlığında dahi postmenopozal retroperitoneal kadınlar da dahil olmak üzere her hastada ayırıcı tanıda akılda tutulması gerektiğidir

Anahtar Kelimeler:

Adneksiyal kitle, paraganglioma, retroperitoneal bölge, menapoz

Nonfunctional Pelvic Retroperitoneal Paraganglioma Mimicking Postmenopausal Adnexal Mass

Paraganglioma is a rare tumor originates from paraganglial tissue which is composed of extraadrenal chromaffin cells. The pelvic and retroperitoneal location of this tumor is extremely rare and it can mimic adnexal mass. The diagnosis of paraganglioma in this region is difficult. The exact diagnosis may only be reached after the total excision and histopathologic examination of the tumor. In this report, for the first time, we presented a postmenopausal woman who had nonfunctional retroperitoneal paraganglioma mimicking postmenopausal adnexal mass. This case emphasizes that extraadrenal paraganglioma should be kept in mind in the differential diagnosis in all patients including postmenopausal woman with retroperitoneal mass even in the presence of nonspecific symptoms like abdominal pain.

Keywords:

Adnexal mass, paraganglioma, retroperitoneal area, menopause,

PDF

___

1. Hasbi S, El Khader A, El Fahssi M, et al. Retroperitoneal nonfunctioning paraganglioma. Can J Surg 2010; 53(1): E3-4.
2. Cunningham SC, Suh HS, Winter JM, Montgomery E, Schulick RD, Cameron JL, et al. Retroperitoneal paraganglioma: single-institution experience and review of the literature. J Gastrointest Surg 2006; 10(8): 1156-63.
3. Somasundar P, Krouse R, Hostetter R, Vaughan R, Covey T. Paragangliomas—a decade of clinical experince. J Surg Oncol 2000;74(4):286-90.
4. Whalen RK, Althausen AF, Daniels GH. Extraadrenal pheochromocytoma. J Urol 1992; 147(1): 1-10.
5. Kuşçu E, Oktem M, Eroglu D, Haberal A, Bilezikci B, Demirhan B. Pelvic retroperitoneal paraganglioma mimicking an ovarian mass. Eur J Gynaecol Oncol 2005;26(2):219-20.
6. Ghidirim G, Rojnoveanu G, Mishin I, Gutsu E, Iakovleva I. Extra-adrenal nonfunctional retroperitoneal paraganglioma: case report and review of the literature. Int Surg 2005; 90(5): 275–8.
7. Chang HC, Lin TC, Lin CM, Chuang FP, Sun GH, Cha TL, et al. Malignant Pelvic Paraganglioma with Bladder Invasion. J Med Sci 2010; 30(3):93-5.