İlhan ÇİFTCİ, Yasar ÜNLÜ, Mustafa Özgür PİRGON

Juvenile granulosa cell tumor and high blood ca-125 levels in children with pseudo-meigs syndrome

Çocuklarda over kist ve tümörleri nadirdir. Yaklaşık olarak solit tümörlerin %1-2 kadarını oluşturur. Over tümörleri üç gruba ayrılır: epitelyal, embrionik ve sex kord stromal tumor. Sex kord stromal tümörler overin central parçasında primordial hücrel- erden oluşur. Biz iki yaşında meme büyümesi şikayeti ile gelen juvenile granüloza hücreli tümörü(JGHT) olan olguyu tespit ettik. Olguda büyük intraabdominal kitle, asit ve sağ hemitoraksta plevral efüzyon mevcuttu. Bu birliktelik Pseudo-Meigs sendromu idi. JGHT ile beraber olan Pseudo-Meigs sendromu oldukça nadir görülmektedir. Bu kadar küçük yaşta literatürde bulunmamaktadır. Sonuç olarak küçük çocukta olsa JGHT ile Pseudo-Meigs sendromu birlikteliği unutulmamalıdır.

Juvenile granüloza hücreli tümörü ve psödo meig sendromlu çocukda yüksek kan ca-125 düzeyi

Ovarian tumors and cysts are rarely seen in children. They constitute 1-2% of solid tumors among children. Over tumors are categorized into three main groups: epithelial, embrionic, and sex cord-stromal tumors. Sex cord-stromal tumors arise from primordial cell cords that are located in the center of the ovary during embriological development. We have detected a patient who was diagnosed with a juvenile granulosa cell tumor (JGCT) at two years of age after presenting with excessive breast enlarge- ment during the past month. She had a large mass in the abdomen, ascites, and marked pleural effusion in the right hemithorax. This association was Pseudo-Meigs syndrome. The association of JGCT and Pseudo-Meigs syndrome is a considerably rare event. Moreover, since the patient was the youngest among all previously reported cases in existing literature, our observations indicate that a juvenile granulosa cell tumor may occur at an early age.In conclusion, Pseudo-Meigs syndrome with JGCT shouldn't forget, even in young children.

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