Yavuz FURUNCUOĞLU, Melih BAŞAR, Süleyman ALICI, Cihan ŞENGÜL

Effects of a Stanol-Enriched Yogurt on Plasma Cholesterol Levels

Plasma kolesterol seviyesini düşürmek için kişiselleştirilmiş diyet uygulamaları ile birlikte bitkisel stanoller tavsiye edilir. Türkiye'de yoğurt tüketimi çok fazla miktarda olmasına rağmen stanollü yoğurtların Türk milletinde yüksek kolesterol değerini düşürüp düşürmediği net belli değildir. Bu konuyu ortaya çıkarmak amacıyla bu çalışma planlanmıştır. Yüksek lipid seviyeli bireylerde, geleneksel akdeniz diyeti ile beraber bitkisel stanollü yoğurt kombinasyonun etkilerini araştırdık. 50 kişi çalışma grubu 50 kişi kontrol grubu olmak üzere 100 hasta çalışmaya dahil edildi. Ne çalışma grubu ne de kontrol grubu kolesterol tedavisi için ilaç almıyordu. Çalışma grubu 100ml stanollü yoğurt alırken kontrol grubu stanolsüz yoğurt aldı. Bütün bireyler akdeniz diyeti yaptı. Stanol grubunda total kolesterol ve LDL kolesterol seviyesi bariz olarak düştü. (%12.9, %14.9 sırasıyla). Kontrol grubunda LDL kolesterolde hafifçe düşme görüldü (%3.3). İki grup arasında Total ve LDL kolesterol deki değişimler oldukça farklıydı (p=0.01). Yüksek lipid seviyeli hastalarda yoğun diyet tedavisine bitkisel stanollerin eklenmesi Total ve LDL kolesterol seviyelerinde düşmeye neden olur

Anahtar Kelimeler:

Kolesterol, diyet, stanol, Türkiye, yoğurt

Effects of a Stanol-Enriched Yogurt on Plasma Cholesterol Levels

Plant stanols have been recommended in combination with individualized dietary interventions to reduce plasma cholesterol concentrations. Even though yogurt is consumed in high quantities in Turkey, it is unclear whether yogurts with plant stanols will reduce high cholesterol levels in a Turkish population. We designed this study to settle this issue. We investigated the effect of plant stanols in yogurt, combined with the traditional Mediterranean diet (TMD), in subjects with high lipid levels. 100 patients were included: 50 in the intervention group and 50 in the control group. Neither the subjects nor the control group were taking any medication for cholesterol. The intervention group received 100 mls of stanol-enriched yogurt, while the control group received the same amount of yogurt without plant stanols. All subjects maintained TMD. Total cholesterol and LDL cholesterol levels decreased significantly in the stanol group (12.9%, 14.9%, respectively). In the control group, a slight decrease in LDL cholesterol (3.3%) was observed. The changes in total and LDL cholesterol between the two groups were significantly different (p=0.01). Intensive dietary intervention with the addition of plant stanols results in a clinically relevant reduction of total and LDL cholesterol in patients with high lipid levels.

Keywords:

Cholesterol, diet, stanol, Turkey, yogurt,

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