Retroperitoneal Extraskeletal Mesenchymal Chondrosarcoma: A Very Rare Case Report

Chondrosarcoma is an uncommon malignant neoplasm of cartilaginous origin. Extraskeletal chondrosarcomas are far less common than their intraosseous counterparts, representing approximately 2% of all soft tissue sarcomas. Clinically, extraskeletal mesenchymal chondrosarcoma (EMC) shows a very fast progression. It also has a high incidence of local recurrence and distant metastasis. The most common locations are the bladder, brain, meninges, mediastinum, and thighs. Other sites, including the retroperitoneum, are very uncommon. The diagnosis of mesenchymal chondrosarcoma can be very challenging, particularly in cases without conspicuous cartilaginous differentiation. In such cases, its distinction from other neoplasms cannot be safely established. Here we present a retroperitoneal tumor diagnosed as EMC in a 73-year-old female.


Anderson JT, Lucas GL. Extraskeletal mesenchymal chondrosarcoma of the forearm: a case report. J Hand Surg Am 2007; 32(3): 389-92. [CrossRef]

Bertoni F, Picci P, Bacchini P, Capanna R, Innao V, Bacci G, et al. Mesenchymal chondrosarcoma of bone and soft tissues. Cancer 1983; 52(3): 533-41. [CrossRef]

Nakashima Y, Unni KK, Shives TC, Swee RG, Dahlin DC. Mesenchy- mal chondrosarcoma of bone and soft tissue: a review of 111 cases. Cancer 1986; 57: 2444-53. [CrossRef]

Seo CY, Jung ST, Byun JW. Extraskeletal Mesenchymal Chondrosar-coma in the Axillary Region: Reports of Two Cases. Korean J Pathol 2012; 46(5): 483-8. [CrossRef]

5. Taori K, Patil P, Attarde V, Chandanshive S, Rangankar V, Rewat-kar N. Primary retroperitoneal extraskeletal mesenchymal chondro-sarcoma: a computed tomography diagnosis. British J Radiol 2007; 80(959): 268-70. [CrossRef]

6. Shapeero LG, Vanel D, Couanet D, Contesso G, Ackerman LV. Ex-traskeletal mesenchymal chondrosarcoma. Radiology 1993; 186(3): 819-26. [CrossRef]

7. Burkill GJC, Healy JC. Anatomy of retroperitoneum. Imaging 2000; 12(1): 10-20. [CrossRef]

8. Ferrario T, Karakousis CP. Retroperitoneal sarcomas: grade and sur-vival. Arch Surg 2003; 138(3): 248-51. [CrossRef]

9. Varma DG. Imaging of soft tissue sarcomas. Curr Oncol Rep 2000; 2(6): 487-90. [CrossRef]

10. Murphey MD, Walker EA, Wilson AJ, Kransdorf MJ, Temple HT, Gannon FH. From the archives of the AFIP: imaging of primary chon-drosarcoma: radiologic-pathologic correlation. Radiographics 2003; 23(5): 1245-78. [CrossRef]

Kaynak Göster