Biyoçözünür İmplant Uygulamaları İçin Saf Çinko Tozlarından İnce Taneli Yapıların İmalatı ve Çözünme Davranışının Karakterizasyonu

Çalışma kapsamında Saf Zn tozlarına Yüksek Basınç Altında Burma (YBAB) uygulanarak ince taneli yapılar elde edilmiştir. 1, 5 ve 10 rotasyondan sonra elde edilen numunelerin, mikro yapıları, mekanik özellikleri ve çözünme davranışları karakterize edilmiştir. Mikro yapı incelemeleri için optik mikroskop, mekanik özellik incelemeleri için sertlik ve çekme testi uygulanmıştır. Çözünme davranışının tespiti için ise vücut sıcaklığında (37 °C) 15 gün boyunca gözlemler gerçekleştirilmiştir. Çözünme testlerinden sonra oluşan yüzey topografyası taramalı elektron mikroskobu (SEM) ile incelenmiştir. Elde edilen sonuçlara göre YBAB işlemi mikro yapıyı, mekanik özellikleri ve çözünme davranışını etkilemiştir. Sertlik 5 rotasyonda en yüksek değere ulaşmış, sonrasında tane toparlanması sebebi ile sertlik değeri düşmüştür. Bunun yanı sıra mekanik dayanım artmaya devam etmiştir. Çözünme davranışı en düşük 10. Rotasyonda elde edilirken bu değerin 5. Rotasyon ile oldukça yakın olduğu gözlemlenmiştir. Bu çalışma ile ilk defa toz Zn başlangıç numunelerinden yola çıkılarak YBAB uygulanmış karakterize edilmiş ve fosfat tamponu içerisinde çözünme davranışı gözlemlenmiştir.

Anahtar Kelimeler:

Biyoçözünür, İmalat, Biyomalzeme, YBAB, UİT, Çözünme davranışı

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