Tofigh TAHERKHANI, Rasool ASGHARI ZAKARIA, Mahboubeh TAHERKHANI

Mutagenic and Anti-mutagenic properties of the essential oil of Jurinea leptoloba DC by Ames Test

ISSN: 2587-2680
Yayın Aralığı: 4
Başlangıç: 2002
Yayıncı: SİVAS CUMHURİYET ÜNİVERSİTESİ > FEN FAKÜLTESİ

Abstract. The aim of this study was to determine the mutagenic and anti-mutagenic properties of the essential oil of Jurinea leptoloba DC in vitro. The mutagenic and anti-mutagenic activities of the oil was evaluated using the Salmonella typhimurium tester strains TA98 and TA100, together with nitrofluorene for TA98 and sodium azide for TA100 without (-S9) metabolic activation, and 2-aminoantracene for TA98 and TA100 with metabolic (+S9) activation. The results obtained with S. typhimurium suggest that the oil of J. leptoloba can not be exploited as an anti-mutagenic agent with low adverse side effects.

Keywords:

Jurinea leptoloba Essential oil, Mutagenic, Anti-mutagenic,

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