Iterated bootstrap procedure in individual bioequivalence
In this paper, we propose an iterating principle in the bootstrap method to assess the individual bioequivalence under 2×4 randomized crossover design. The finite sample properties of the proposed algorithm are illustrated by an extensive simulation study and a real-world example. Our findings reveal that the proposed idea have better performance than the classical percentile bootstrap confidence limits.
Keywords:
Bioequivalence, bootstrap hypothesis testing,
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- ISSN: 1303-5991
- Yayın Aralığı: Yılda 4 Sayı
- Başlangıç: 1948
- Yayıncı: Ankara Üniversitesi