Tuberculous meningitis in a patient with systemic lupus erythematosus

Sistemik lupus eritematozus (SLE), çeşitli organları etki- leyen, etyolojisi bilinmeyen, kronik inflamatuvar otoim- mün bir hastalıktır. Sistemik lupus eritematozuslu hasta- larda morbidite ve mortalitenin önemli bir sebebi enfek- siyonlardır. Enfeksiyon için risk faktörleri arasında, siste- mik lupus eritematozusa ya da immünosüpresif ve sitotoksik tedaviye bağlı immün sistemdeki bozukluk yer alır. İmmün sistemde meydana gelen anormallikler ve kullanılan immünosüpresif tedaviye bağlı olarak enfeksiyonlar sık ve farklı spektrumda görülmektedir. Bu olgu, sistemik lupus eritematozus tanısıyla izlenen has- talarda merkezi sinir sistemi ile ilgili patolojilerde tüber- küloz menenjitin ayırıcı tanıda akla gelmesi için sunul- muştur.

Sistemik lupus eritematozuslu hastada tüberküloz menenjit

Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease of unknown etio- logy that affects various organs. In patients with SLE, infections are the most important causes of morbidity and mortality. Their risk factors for infection include immune system irregularities due to SLE and immu- nosuppressive/cytotoxic therapy. Infection is fre- quent and the unusual spectrum of organisms is thought to be related to the combined effect of immune system anomalies and immunosuppressive therapy. This case is presented to remind us that tuberculous meningitis should be included in the dif- ferential diagnosis of central nervous system patholo- gies in patients diagnosed with SLE.

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Kaynak Göster

Çocuk Enfeksiyon Dergisi
  • ISSN: 1307-1068
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2006
  • Yayıncı: Yeliz İşitmir

6.3b5.3b

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