Çocuklarda besin ve mantar zehirlenmeleri

Besin zehirlenmeleri patojenik mikroorganizmalar, toksinler ya da kimyasal maddelerle kontamine olmuş besin ya da su tüketilmesi ile meydana gelen ve sporadik ya da epidemik olarak ortaya çıkabilen hastalıklardır. Çoğu zaman özgün bir tedavi gerektirmeksizin kendini sınırlayan ve hızlı iyileşmeyle sonlanan gastrointestinal belirtilerle seyretse de ağır mantar zehirlenmesinde olduğu gibi hastaneye yatış ve yoğun tedavi gerektiren morbidite ve mortalitesi yüksek klinik tablolar ortaya çıkabilmektedir. Bu yazıda çocuklarda besin ve mantar zehirlenmelerinde epidemiyoloji, tanı, tedavi, korunma ve önleme yöntemlerinin gözden geçirilmesi amaçlanmıştır.

Food and mushroom poisonings in children

Food borne diseases may occur as a result of food or water intake contaminated by pathogenic microorganisms, toxins or chemical substances. They may occur sporadically or epidemically. Although these diseases follow a course of self-limiting and rapid healing gastrointestinal symptoms in most cases, clinical situations with high mortality and morbidity risk such as serious mushroom poisoning, which requires hospitalization and intensive care, are also likely to happen. The aim of this study is to evaluate methods used in the epidemiology, diagnosis, treatment, protection and prevention of food and mushroom poisoning in children.

Kaynakça

1. T.C.S.B Araştırma, Planlama ve Koordinasyon Kurulu Başkanlığı. Sağlık İstatistikleri. Ankara; 2004.

2. Bhutta AZ. Acute Gastroenteritis in Children. In: Behrman RE, Kliegman RM, Jenson HB, (eds). Nelson Textbook of Pediatrics. 18th ed. Philadelphia: W.B. Saunders Company 2004, p.1605-20.

3. Department of Health and Human Services Centers for Disease Control and Prevention. Diagnosis and Management of Foodborne Illnesses. Morbidity and Mortality Weekly Report 2004; 53: 1-33.

4. Tauxe RV, Swerdlow DL, Hughes JM. Foodborne disease. In: Mandell GL, Bennett JE, Dolin R (eds). Principles and Practice of Infectious Disease. 5th edition. Philadelphia: Churchill Livingstone 2000, p.1150-60.

5. Report of the Committee on Infectious Diseases. Red-Book. Twenty-sixth ed. Nourthwest: American Academy of Pediatrics 2003, p.212-43.

6. Yafet Aji D. Besin Zehirlenmeleri. İ.Ü Cerrahpaşa Sürekli Tıp Eğitimi Etkinlikleri Yaz İshalleri-Besin Zehirlenmeleri Sempozyumu. 1. Baskı. İstanbul: Deomed Medikal Yayıncılık 1998, s.153-62.

7. http://www.foodsafety.gov/~mow/intro.html, “Bad Bug Book. Foodborne Pathogenic Microorganisms and Natural Toxins Handbook”, FDA Center for Food Safety & Applied Nutrition, 22.01.2009.

8. Yafet Aji D, İlter Ö. Türkiye'de çocuk zehirlenmeleri. Türk Pediatri Arşivi 1998; 33: 154-58.

9. Altunyuva S, Besli E, Öcal S, Ceyhan İ, Çakı S, Erten M. ve ark. Çocukluk çağında zehirlenmeler. SSK Vakıf Gureba Hastanesi Dergisi 2004; 2: 114-8.

10. Bower JR. Foodborne Diseases: Shiga Toxin Producing E. Coli (STEC). Pediatr Infect Dis J 1999; 18(10): 909-10.

11. Rose JB, Slifko TR. Giardia, Cryptosporidium and Cyclospora and Their Impact on Foods: A Review. J. Food Prot 1999; 62: 1059-70.

12. Rowe SY, Rocourt JR, Shiferaw B, Kassenborg HD, Segler SD, Marcus R et al. Breast-feeding decreases the risk of sporadic salmonellosis among infants in FoodNet sites.Clin Infect Dis 2004; 15: 62-70.

13. Mat A. Türkiye'de Mantar Zehirlenmeleri ve Zehirli Mantarlar. 2. Baskı. İstanbul: Nobel Tıp Kitapevleri; 2000, s.173-86.

14. Ünlüoğlu I, Tayfur M. Mushroom poisoning: an analysis of the data between 1996 and 2000. Eur J Emerg Med 2003; 10: 23-6.

15. James HD. Syndromic diagnosis and management of confirmed mushroom poisonings. Crit Care Med 2005; 33(2): 427-36.

16. Saltık İN, Sarıkayalar F. Mantar Zehirlenmesi ve Tedavisi. Katkı Pediatri Dergisi 2001; 22: 534-40.

17. Yafet Aji D. Çocukluk Çağında Zehirlenmeler ve Mantar Zehirlenmesi. İ.Ü Cerrahpaşa Sürekli Tıp Eğitimi Etkinlikleri Pediatrik Aciller Sempozyumu. 1. Baskı. İstanbul: Deomed Medikal Yayıncılık 2001, s.69-78.

18. Crystal NB, Anjana A, Sean RL, Anthony BP, Gramlich T, Henderson M et al. Mushroom Poisoning- From Diarrhea to Liver Transplantation. Am J of Gastroenterol 2001; 96: 3195-8.

19. Mas A. Mushrooms, amatoxins and the liver. J of Hepatol 2005; 42: 166-9.

20. Enjalbert F, Rapior S, Nouguier-Soule J, Guillon S, Amouroux N, Cabot C. Treatment of Amatoxin Poisoning: 20-Year Retrospective Analysis. J Clin Toxicol 2002; 40: 715-57.

21. Ergüven M, Çakı S, Deveci M. Mantar zehirlenmesi: 28 vakanın değerlendirilmesi. Çocuk Sağlığı ve Hastalıkları Dergisi 2004; 47: 249-53.

22. Yafet Aji D, Çalişkan S, Nayir A. Haemoperfusion in amanita phalloides poisoning. J Trop Pediatr 1995; 41: 371-4.

23. Karakullukcu F, Besler M, Yurdun T, Sifoglu Z, Yüksel K, Hacikaptan E et al. Hemoperfusion Is Life Saving in Amanita phalloides Intoxication. XXXIII. Congress of EDTA, 11-14 Nov 1996, Amsterdam, Holland, Abstract Book, p.316, 1996.

24. Rubik J, Pietraszek E, Kaminski A. Successful treatment of a child with fulminant liver failure and coma caused by Amanita Phalloides intoxication with albumin dialysis without liver transplantation. Pediatr Transplant 2004; 8: 295-300.

25. Covic A, Goldsmith DJA, Gusbeth-Tatomir P, Volovat C, Dimitriu AG, Cristogel F et al. Succesfull use of Moleculer Adsorbent Regenerating System (MARS) dialysis for the treatment of fulminant hepatic failure in children accidentally poisoned by toxic mushroom ingestion. Liver International 2003; 23: 21-7.

26. Ganzert M, Felgenhauer N, Zilker T. Indication of liver transplantation following amatoxin intoxication. J of Hepatol 2005; 42: 202-9.

27. Scott E. Relationship between cross-contamination and the transmission of foodborne pathogens in the home. Pediatr Infect Dis J 2000; 19: 111-3.

28. Midura TF. Update: İnfant botulism. Clin Microbiol Rev 1996; 9 (2): 119-25.

29. Food Standarts Agency Publications. Preventing food poisoning. England; 2002.

Kaynak Göster