COMMON VARIABLE IMMUNODEFICIENCY AT ADULT AGE

Common Variable Immunodeficiency (CVID) is a heterogeneous group of diseases progressing with recurrent infections. This disease should be considered in cases experiencing recurrent lung infection, otitis media, rhinosinusitis, and urinary tract infection. Since it is generally seen in the childhood age group, the diagnosis in adults may be delayed. A Common Variable Immunodeficiency case, which was followed up in our clinic and characterized by recurrent upper respiratory tract infection and pneumonia, was presented to raise awareness on this issue. CVID should be kept in mind in patients who are admitted to outpatient clinics with recurrent infections, who do not respond despite appropriate treatments, and who develop complications.

___

  • 1. MUŞABAK UH, Demirel F, YEŞİLLİK S, et al. Adults with common variable immunodeficiency: a singlecenter experience. Turkish journal of medical sciences. 2017;47(1):1-12.
  • 2. Yazdani R, Habibi S, Sharifi L, et al. Common variable immunodeficiency: epidemiology, pathogenesis, clinical manifestations, diagnosis, classification, and management. Journal of investigational allergology & clinical immunology. 2020;30(1):14-34.
  • 3. Cunningham-Rundles C. How I treat common variable immune deficiency. Blood. 2010;116(1):7-15.
  • 4. Ardeniz Ö, Kaçmaz Basoglu O, Günsar F, et al. 8 Clinical and Immunological Analysis of 23 Adult Patients With Common Variable Immunodeficiency. Journal of investigational allergology & clinical immunology. 2010;20(3):222.
  • 5. Salepci BM, TAHTASAKAL SD, KIRAL N, et al. İki Olgu Nedeniyle Ampiyem ile Ortaya Çıkan Yaygın Değişken İmmün Yetmezlik Sendromu.